Experimental Evaluation and Modeling of Adsorption Phenomena of Nanoliposomes on Poly(dimethylsiloxane) Surfaces

被引：0

作者：

Koyagura, Sylvan Sunny ^{[1
]}

Majarikar, Virendra ^{[1
]}

Takehara, Hiroaki ^{[1
,2
]}

Ichiki, Takanori ^{[1
,2
]}

机构：

[1] Univ Tokyo, Sch Engn, Dept Mat Engn, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138656, Japan

[2] Innovat Ctr NanoMed iCONM, 3-25-14 Tonomachi, Kawasaki, Kanagawa 2100821, Japan

来源：

JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY | 2021年 / 34卷 / 01期

基金：

日本科学技术振兴机构;

关键词：

Solid surface adsorption; Analytical model; Non-equilibrium adsorption; nanoliposome; PDMS microchannel; CHIP;

D O I：

10.2494/photopolymer.34.1

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Nanoparticles, such as exosomes or liposomes, have been widely studied using poly(dimethylsiloxane) (PDMS) microchannels. The interaction between nanoparticles and solid surfaces is an important subject for basic and applied research on nanoparticles, but there have been few reports on the use of microchannels for this purpose. Micro-scale systems serve as a useful platform for adsorption analysis because of their large surface-to-volume ratio. In this study, we attempted to develop a platform to study the adsorption phenomena of nanoparticles on solid surfaces using a microchannel, in which a model that analyzes dynamic (i.e., non-equilibrium) adsorption was used. This model allowed quantitative analysis of nanoliposome adsorption onto the surface of a PDMS microchannel.

引用

页码：1 / 5

页数：5

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