Inter-individual variability in the catalytic activity of CYP3A4 per unit of enzyme (kcat)

被引:0
|
作者
Lei, Y [1 ]
Wilson, ZE [1 ]
Crewe, KH [1 ]
Tucker, GT [1 ]
Rostami-Hodjegan, A [1 ]
机构
[1] Univ Sheffield, Acad Unit Clin Pharmacol, Sheffield, S Yorkshire, England
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
116
引用
收藏
页码:54 / 54
页数:1
相关论文
共 50 条
  • [31] Identification and characterization of CYP3A4*20, a novel rare CYP3A4 allele without functional activity
    Westlind-Johnsson, A
    Hermann, R
    Huennemeyer, A
    Hauns, B
    Lahu, G
    Nassr, N
    Zech, K
    Ingelman-Sundberg, M
    von Richter, O
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2006, 79 (04) : 339 - 349
  • [32] Identification of baseline parameters associated with the inter-individual variability in cytidine deaminase serum activity, a key enzyme in the metabolism of pyrimidine analogue
    Cohen, Romain
    Preta, Laure-Helene
    Bessone, Aurelia
    Narjoz, Celine
    Nicolis, Ioannis
    Desaulle, Dorota
    Curis, Emmanuel
    Cessot, Anatole
    Huillard, Olivier
    Thomas-Schoemann, Audrey
    Vidal, Michel
    Goldwasser, Francois
    Alexandre, Jerome
    Blanchet, Benoit
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [33] Effect of influenza immunization on CYP3A4 activity
    Hayney, MS
    Hammes, RJ
    Fine, JP
    Bianco, JA
    VACCINE, 2001, 20 (5-6) : 858 - 861
  • [34] A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism
    Dorne, Jean Lou C. M.
    Cirlini, Martina
    Louisse, Jochem
    Pedroni, Lorenzo
    Galaverna, Gianni
    Dellafiora, Luca
    TOXINS, 2022, 14 (03)
  • [35] Evaluation of the genetic component of variability in CYP3A4 activity:: a repeated drug administration method
    Özdemir, V
    Kalow, W
    Tang, BK
    Paterson, AD
    Walker, SE
    Endrenyi, L
    Kashuba, ADM
    PHARMACOGENETICS, 2000, 10 (05): : 373 - 388
  • [36] Effect of NIPRISANA® on CYP3A4 activity in vitro
    Adzu, Bulus
    Masimirembwa, Collen
    Mustapha, Kudirat Bola
    Thelingwani, Roslyn
    Kirim, Rukaiyatu Abdullahi
    Gamaniel, Karniyus Shingu
    EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2015, 40 (01) : 115 - 118
  • [37] Effects of metronidazole on hepatic CYP3A4 activity
    Haas, CE
    Kaufman, DC
    DiCenzo, RC
    PHARMACOTHERAPY, 2001, 21 (10): : 1192 - 1195
  • [38] Characterization of the modulation of the CYP3A4 activity by Efavirenz
    Hariparsad, N
    Nallani, SC
    Desai, PB
    DRUG METABOLISM REVIEWS, 2003, 35 : 79 - 79
  • [39] Effect of medical castration on CYP3A4 enzyme activity using the erythromycin breath test
    Hutson, Paul R.
    Oettel, Kurt
    Douglas, Jeff
    Ritter, Mark
    Messing, Ed
    Staab, Mary Jane
    Alberti, Dona
    Horvath, Dorthea
    Wilding, George
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2008, 62 (03) : 373 - 377
  • [40] Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans
    Perera, M. A.
    Thirumaran, R. K.
    Cox, N. J.
    Hanauer, S.
    Das, S.
    Brimer-Cline, C.
    Lamba, V.
    Schuetz, E. G.
    Ratain, M. J.
    Di Rienzo, A.
    PHARMACOGENOMICS JOURNAL, 2009, 9 (01): : 49 - 60