MEDI 286-Synthesis and structure activity relationship of novel azaurazil and pyridopyramidine derivatives of arylpiperazine as potential and selective 5-Ht1a receptor agonists

被引：0

作者：

Majo, Vattoly J. ^{[1
]}

Prabhakaran, Jaya ^{[1
]}

Savenkova, Lyudmila ^{[1
]}

Mann, J. John ^{[1
,2
,3
]}

Kumar, J. S. Dileep ^{[1
,2
,3
]}

机构：

[1] Columbia Univ, Dept Psychiat, New York, NY 10032 USA

[2] Columbia Univ, Div Neurosci, New York, NY 10032 USA

[3] New York State Psychiat Inst & Hosp, New York, NY 10032 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 234卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

286-MEDI

引用

页数：1

共 50 条

[21] 5-HT2A receptor inverse-agonists:: Design and structure-activity relationship of novel pyrazole derivatives
Strah-Pleynet, Sonja
Teegarden, Bradley R.
Selaya, Susan D.
Thomsen, William
Reyes, Hazel
Foster, Jonathan
Menzaghi, Frederique
Whelan, Kevin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
[22] Synthesis, SAR studies, and evaluation of 1,4-benzoxazepine derivatives as selective 5-HT1A receptor agonists with neuroprotective effect:: Discovery of Piclozotan
Kamei, K
Maeda, N
Nomura, K
Shibata, M
Katsuragi-Ogino, R
Koyama, M
Nakajima, M
Inoue, T
Ohno, T
Tatsuoka, T
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (06) : 1978 - 1992
[23] POLYCYCLIC ARYLPIPERAZINYL AND HETEROARYLPIPERAZINYL IMIDES AS 5-HT1A RECEPTOR LIGANDS AND POTENTIAL ANXIOLYTIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES
ABOUGHARBIA, M
PATEL, UR
WEBB, MB
MOYER, JA
ANDREE, TH
MUTH, EA
JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (07) : 1382 - 1392
[24] Novel 5-HT1A receptor agonists exhibit analgesic activity in different models of acute and neuropathic pain
Szczepan Mogilski
Anna Czopek
Kinga Sałat
Monika Kubacka
Monika Dyląg
Barbara Filipek
Pharmacological Reports, 2013, 65 (Suppl 1) : 68 - 68
[25] Design and Synthesis of Piperazinylpyridine Derivatives as Novel 5-HT1A Agonists/5-HT3 Antagonists for the Treatment of Irritable Bowel Syndrome (IBS)
Asagarasu, Akira
Matsui, Teruaki
Hayashi, Hiroyuki
Tamaoki, Satoru
Yamauchi, Yukinao
Sato, Michitaka
CHEMICAL & PHARMACEUTICAL BULLETIN, 2009, 57 (01) : 34 - 42
[26] Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands
Siracusa, Maria A.
Salerno, Loredana
Modica, Maria N.
Pittala, Valeria
Romeo, Giuseppe
Amato, Maria E.
Nowak, Mateusz
Bojarski, Andrzej J.
Mereghetti, Ilario
Cagnotto, Alfredo
Mennini, Tiziana
JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (15) : 4529 - 4538
[27] Design and synthesis of a series of 6-substituted-2-pyridinylmethylamine derivatives as novel, high-affinity, selective agonists at 5-HT1A receptors
Vacher, B
Bonnaud, B
Funes, P
Jubault, N
Koek, W
Assié, MB
Cosi, C
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (25) : 5070 - 5083
[28] MEDI 391-Synthesis and structure activity relationship of novel spiro-isobenzofuranone derivatives as potent, brain penetrable and selective histamine H3 receptor inverse agonists
Jitsuoka, Makoto
Tsukahara, Daisuke
Ito, Sayaka
Mitobe, Yuko
Miyamoto, Yasuhisa
Yoshimoto, Ryo
Tanaka, Takeshi
Takenaga, Norihiro
Tokita, Shigeru
Sato, Nagaaki
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
[29] Design, synthesis, and structure-activity relationship of novel opioid κ receptor selective agonists: α-Iminoamide derivatives with an azabicyclo[2.2.2]octene skeleton
Watanabe, Yoshikazu
Kitazawa, Shota
Fujii, Hideaki
Nemoto, Toru
Hirayama, Shigeto
Iwai, Takashi
Gouda, Hiroaki
Hirono, Shuichi
Nagasea, Hiroshi
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (21) : 4980 - 4983
[30] Solid-supported synthesis, molecular modeling, and biological activity of long-chain arylpiperazine derivatives with cyclic amino acid amide fragments as 5-HT7 and 5-HT1A receptor ligands
Canale, Vittorio
Guzik, Pawel
Kurczab, Rafal
Verdie, Pascal
Satala, Grzegorz
Kubica, Bartlomiej
Pawlowski, Maciej
Martinez, Jean
Subra, Gilles
Bojarski, Andrzej J.
Zajdel, Pawel
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 78 : 10 - 22

← 1 2 3 4 5 →