EFFECTS OF OCT2 AND MATE1 POLYMORPHISMS AND INHIBITION BY TRIMETHOPRIM ON METFORMIN PHARMACOKINETICS.

被引：0
|
作者：
Czock, D. [1 ]
Grun, B. [1 ]
Kiessling, M. [1 ]
Burhenne, J. [1 ]
Riedel, K. [1 ]
Weiss, J. [1 ]
Rauch, G. [2 ]
Haefeli, W. E. [1 ]
机构：
[1] Univ Heidelberg Hosp, Heidelberg, Germany
[2] Univ Heidelberg, Heidelberg, Germany
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2012年 / 91卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：S63 / S64
页数：2
相关论文
共 50 条
  • [21] The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin
    Stocker, S. L.
    Morrissey, K. M.
    Yee, S. W.
    Castro, R. A.
    Xu, L.
    Dahlin, A.
    Ramirez, A. H.
    Roden, D. M.
    Wilke, R. A.
    McCarty, C. A.
    Davis, R. L.
    Brett, C. M.
    Giacomini, K. M.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 93 (02) : 186 - 194
  • [22] Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
    Eriko Shikata
    Rei Yamamoto
    Hiroshi Takane
    Chiaki Shigemasa
    Tadasu Ikeda
    Kenji Otsubo
    Ichiro Ieiri
    Journal of Human Genetics, 2007, 52 : 117 - 122
  • [23] Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
    Shikata, Eriko
    Yamamoto, Rei
    Takane, Hiroshi
    Shigemasa, Chiaki
    Ikeda, Tadasu
    Otsubo, Kenji
    Ieiri, Ichiro
    JOURNAL OF HUMAN GENETICS, 2007, 52 (02) : 117 - 122
  • [24] Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters
    Reznicek, Josef
    Ceckova, Martina
    Cerveny, Lukas
    Mueller, Fabian
    Staud, Frantisek
    XENOBIOTICA, 2017, 47 (01) : 77 - 85
  • [25] Thioacetamide-Induced Acute Liver Injury Increases Metformin Plasma Exposure by Downregulating Renal OCT2 and MATE1 Expression and Function
    Zhi, Hao
    Dai, Yidong
    Su, Lin
    Yang, Lu
    Wu, Wenhan
    Wang, Zehua
    Zhu, Xinyue
    Liu, Li
    Aa, Jiye
    Yang, Hanyu
    BIOMEDICINES, 2023, 11 (12)
  • [26] A Physiologically-Based Pharmacokinetic Model of Trimethoprim for MATE1, OCT1, OCT2, and CYP2C8 Drug-Drug-Gene Interaction Predictions
    Tuerk, Denise
    Hanke, Nina
    Lehr, Thorsten
    PHARMACEUTICS, 2020, 12 (11) : 1 - 19
  • [27] Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells
    Zhang, Xiaohong
    Wright, Stephen H.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
  • [28] The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin
    Tzvetkov, M. V.
    Vormfelde, S. V.
    Balen, D.
    Meineke, I.
    Schmidt, T.
    Sehrt, D.
    Sabolic, I.
    Koepsell, H.
    Brockmoeller, J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2009, 86 (03) : 299 - 306
  • [29] A NOVEL OCT2/OCT3/MATE1 TRIPLE EXPRESSION MODEL FOR STUDYING ACTIVE CREATININE EXCRETION IN THE KIDNEY
    Huang, Yong
    Kosaka, Alan
    Huang, Jane
    Warren, Mark S.
    Zhang, John
    DRUG METABOLISM REVIEWS, 2012, 44 : 142 - 142
  • [30] Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity
    Yokoo, Sachiko
    Yonezawa, Atsushi
    Masuda, Satohiro
    Fukatsu, Atsushi
    Katsura, Toshiya
    Inui, Ken-Ichi
    BIOCHEMICAL PHARMACOLOGY, 2007, 74 (03) : 477 - 487
12345