Methadone-induced QTc prolongation:: Is it due to stereoselective block of hERG or to inappropriate QTc interval correction?

被引:2
|
作者
Andrassy, G. [1 ]
Szabo, A. [2 ]
机构
[1] Szent Ferenc Korhaz, Dept Cardiol, Budapest, Hungary
[2] Univ Pecs, Fac Nat Sci, Pecs, Hungary
关键词
D O I
10.1038/sj.clpt.6100329
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:671 / 671
页数:1
相关论文
共 50 条
  • [31] DEXTROPROPOXYPHENE INDUCED QTC INTERVAL PROLONGATION: CORRELATION BETWEEN ELECTROCARDIOGRAPHIC MEASUREMENTS AND PLASMA CONCENTRATIONS
    Keller, G.
    Quiroga, P.
    Olivera, N.
    Fernandez, N.
    Schimpl, A.
    Diez, R.
    Girolamo, G. D.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 115 : 17 - 17
  • [32] Genome-wide association study of antipsychotic-induced QTc interval prolongation
    Aberg, K.
    Adkins, D. E.
    Liu, Y.
    McClay, J. L.
    Bukszar, J.
    Jia, P.
    Zhao, Z.
    Perkins, D.
    Stroup, T. S.
    Lieberman, J. A.
    Sullivan, P. F.
    van den Oord, E. J. C. G.
    PHARMACOGENOMICS JOURNAL, 2012, 12 (02): : 165 - 172
  • [33] Challenges of characterizing proarrhythmic risk due to QTc prolongation induced by nonadjuvant anticancer agents
    Sarapa, Nenad
    Britto, Margaret R.
    EXPERT OPINION ON DRUG SAFETY, 2008, 7 (03) : 305 - 318
  • [34] Risk assessment for antimicrobial agent-induced QTc interval prolongation and torsades de pointes
    Owens, RC
    PHARMACOTHERAPY, 2001, 21 (03): : 301 - 319
  • [35] Tramadol Induced QTc-Interval Prolongation: Prevalence, Clinical Factors and Correlation to Plasma Concentrations
    Keller, Guillermo A.
    Etchegoyen, Maria C. V.
    Fernandez, Nicolas
    Olivera, Nancy M.
    Quiroga, Patricia N.
    Belloso, Waldo H.
    Diez, Roberto A.
    Di Girolamo, Guillermo
    CURRENT DRUG SAFETY, 2016, 11 (03) : 206 - 214
  • [36] Oxatomide-Induced QTc Interval Prolongation in Pediatric Patients After Single and Repeated Overdose
    Contessa, M. G.
    Petrolini, V
    Vecchio, S.
    Rognoni, C.
    Giampreti, A.
    Lonati, D.
    Bigi, S.
    Locatelli, C.
    Manzo, L.
    CLINICAL TOXICOLOGY, 2010, 48 (03) : 295 - 295
  • [37] Stereoselective block of hERG channel by (S)-methadone and QT interval prolongation in CYP2B6 slow metabolizer:: Evidence of a safer cardiac profile of (R)-methadone
    Eap, C. B.
    Crettol, S.
    Rougier, J. S.
    Schlaepfer, J.
    Sintra, Grilo, I
    Deglon, J. J.
    Besson, J.
    Croquette-Krokar, M.
    Carrupt, P. A.
    Abriel, H.
    PHARMACOPSYCHIATRY, 2008, 41 (05) : 207 - 208
  • [38] COMPARISON OF QTc INTERVAL PROLONGATION FOR PATIENTS IN METHADONE VERSUS BUPRENORPHINE MAINTENANCE TREATMENT: A 5-YEAR FOLLOW-UP
    Fareed, Ayman
    Patil, Dustin
    Scheinberg, Kelly
    Gale, Robin Blackinton
    Vayalapalli, Sreedevi
    Casarella, Jennifer
    Drexler, Karen
    JOURNAL OF ADDICTIVE DISEASES, 2013, 32 (03) : 244 - 251
  • [39] Translating the gap in the evaluation of drug-induced QTc-interval prolongation from in vivo to the clinic
    Dubois, Vincent F. S.
    van der Graaf, Piet
    Leishman, Derek
    Gallacher, David
    McMahon, Nick
    Visser, Sandra
    Danhof, Meindert
    Della Pasqua, Oscar
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2014, 70 (03) : 324 - 324
  • [40] Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans
    V. F. S. Dubois
    W. E. A. de Witte
    S. A. G. Visser
    M. Danhof
    O. Della Pasqua
    Pharmaceutical Research, 2016, 33 : 40 - 51