MITOCHONDRIAL HEXOKINASE II IS ESSENTIAL FOR CARDIAC FUNCTION AND ISCHAEMIC PRECONDITIONING

被引:0
|
作者
Smeele, K. M. [1 ]
Southworth, R. [2 ]
Wu, R. [3 ]
Xie, C. [4 ]
Nederlof, R. [1 ]
Warley, A. [2 ]
Koeman, A. [1 ]
Eerbeek, O. [5 ]
Akar, F. [4 ]
Ardehali, H. [3 ]
Hollmann, M. W. [1 ]
Zuurbier, C. J. [1 ]
机构
[1] AMC, Dept Anesthesiol, Amsterdam, Netherlands
[2] Kings Coll London, Dept Imaging Chem & Biol, London WC2R 2LS, England
[3] Northwestern Univ, Dept Med, Chicago, IL 60611 USA
[4] Dept Pharmacol, New York, NY USA
[5] AMC, Dept Physiol, Amsterdam, Netherlands
关键词
D O I
10.1136/heartjnl-2011-301156.7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Effects of propionyl-carnitine on mitochondrial respiration and post-ischaemic cardiac function in the ischaemic underperfused diabetic rat heart
    Broderick T.L.
    Paulson D.J.
    Gillis M.
    Drugs in R & D, 2004, 5 (4) : 191 - 201
  • [32] Effects of remote ischaemic preconditioning on clinical outcomes after cardiac surgery
    Xue, Fu Shan
    Li, Rui Ping
    Cui, Xin Long
    HEART, 2015, 101 (16) : 1346 - 1346
  • [33] Activation of α1-adrenoceptors is not essential for the mediation of ischaemic preconditioning in rat heart
    Vasara, E
    Seraskeris, S
    Lazou, A
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2002, 29 (1-2) : 11 - 17
  • [34] An investigation into the effects of simulated ischaemic preconditioning on mitochondrial fusion in mouse embryonic fibroblasts
    Ernest J Chew
    Andrew R Hall
    Niall F Burke
    Derek J Hausenloy
    Derek Yellon
    Journal of Cardiothoracic Surgery, 10 (Suppl 1)
  • [35] Trimetazidine (TMZ) abolishes drug-induced and attenuates ischaemic preconditioning - further support for a mitochondrial role in preconditioning
    van den Bos, EJ
    Minners, J
    Opie, LH
    Sack, MN
    EUROPEAN HEART JOURNAL, 2000, 21 : 671 - 671
  • [36] Does remote ischaemic preconditioning with postconditioning improve clinical outcomes of patients undergoing cardiac surgery? Remote Ischaemic Preconditioning with Postconditioning Outcome Trial
    Hong, Deok Man
    Lee, Eun-Ho
    Kim, Hyun Joo
    Min, Jeong Jin
    Chin, Ji-Hyun
    Choi, Dae-Kee
    Bahk, Jae-Hyon
    Sim, Ji-Yeon
    Choi, In-Cheol
    Jeon, Yunseok
    EUROPEAN HEART JOURNAL, 2014, 35 (03) : 176 - +
  • [37] Involvement of free radicals and mitochondrial K+ATP channels in ischaemic preconditioning depends critically on the preconditioning stimulus
    Liem, DA
    Heinen, A
    Bos, WEM
    van den Heuvel, R
    Verdouw, PD
    Duncker, DJ
    EUROPEAN HEART JOURNAL, 2002, 23 : 636 - 636
  • [38] DISRUPTION OF HEXOKINASE II-MITOCHONDRIAL BINDING AFFECTS CARDIAC OXYGEN CONSUMPTION AND LACTATE PRODUCTION IN THE BEATING HEART
    Nederlof, R.
    Gurel, E.
    Koeman, A.
    Hollmann, M. W.
    Southworth, R.
    Zuurbier, C. J.
    HEART, 2011, 97 (24)
  • [39] Preconditioning and postconditioning: The essential role of the mitochondrial permeability transition pore
    Lim, Shiang Y.
    Davidson, Sean M.
    Hausenloy, Derek J.
    Yellon, Derek M.
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 : S171 - S171
  • [40] SPECIFICITY OF THE INTERACTION OF ISOZYME II OF HEXOKINASE WITH MITOCHONDRIAL-MEMBRANES
    MUNTYAN, EM
    GONCHAROVA, NY
    BIOCHEMISTRY-MOSCOW, 1986, 51 (03) : 333 - 341