The Synthesis and Spectral Properties of Some New Monomethine Cyanine Dyes for Live Cell Imaging

被引：0
|
作者：
Fu, Y. L. [1 ]
Dong, S. Y. [1 ]
Zhou, Y. Z. [1 ]
Zhang, G. [1 ]
Yang, Q. C. [1 ]
Zhai, X. [2 ]
Wang, L. Y. [3 ]
机构：
[1] Xian Univ Architecture & Technol, Sch Sci, Xian 710055, Peoples R China
[2] Northwest Inst Mech & Elect Engn, Xianyang 712099, Peoples R China
[3] Northwest Univ, Coll Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2015年 / 36卷 / 02期
关键词：
Synthesis; Monomethine cyanine dyes; UV-Vis; Live cell imaging; FLUORESCENCE; PROBES; DNA; MICROSCOPY; DENSITY;
D O I：
10.1002/bkcs.10110
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Four monomethine cyanine dyes were synthesized and their structures were confirmed by H-1 NMR, IR, UV-Vis, and HRMS. Their spectral properties were studied. It could be found that the lambda(max) of the dyes was shorter in the protonic solvents compared with that in the non-protonic solvents. Moreover, the lambda(max) shows a hypsochromic shift with the increasing polarity of the solvents. The interactions of four dyes with DNA were also studied. The results showed that the fluorescence intensities of the dyes 3a and 3b took place a qualitative change in the presence of DNA compared with the free dyes. The dyes used as cellular imaging agents were researched. The results indicated that the dye 3b could penetrate the live cell membrane.
引用
收藏
页码：578 / 582
页数：5
相关论文
共 50 条
  • [41] Synthesis of novel tetracationic asymmetric monomeric monomethine cyanine dyes - highly fluorescent dsDNA probes
    Vasilev, Aleksey
    Deligeorgiev, Todor
    Kaloyanova, Stefka
    Stoyanov, Stanimir
    Maximova, Vera
    Vaquero, Juan J.
    Alvarez-Builla, Julio
    COLORATION TECHNOLOGY, 2011, 127 (01) : 69 - 74
  • [42] Microwave-Assisted Synthesis and Spectral Properties of Some Benzoindohemicyanine and Benzoindodimethine Cyanine Dyes as well as the Interaction with Biomolecules
    Kang, Qiong
    Fan, Fangli
    Bi, Weibin
    Huang, Yi
    Fu, Yile
    Wang, Lanying
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2012, 32 (03) : 567 - 573
  • [43] SYNTHESIS OF SOME NEW UNSYMMETRICAL AZA-PYRAZOLOMONOMETHINE CYANINE DYES
    ELKASHEF, HS
    ELSHAFEI, AK
    ELKHAWAGA, AM
    JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 1982, 32 (02) : 412 - 415
  • [44] Microwave-assisted solvent-free synthesis and spectral properties of some dimethine cyanine dyes as fluorescent dyes for DNA detection
    Zhang, Xiang-Han
    Wang, Lan-Ying
    Nan, Zhi-Xiang
    Tan, Shi-Huan
    Zhang, Zu-Xun
    DYES AND PIGMENTS, 2008, 79 (02) : 205 - 209
  • [45] Synthesis and physicochemical studies of some new quinolinoxazine pentamethine cyanine dyes
    Abd El-Aal, R. M.
    Saber, N. M.
    Mina, S. M.
    Essam, Z. M.
    ARABIAN JOURNAL OF CHEMISTRY, 2017, 10 (01) : 82 - 90
  • [46] Novel quinone cyanine dyes: synthesis and spectral studies
    Shindy, HA
    El-Maghraby, MA
    Eissa, FM
    DYES AND PIGMENTS, 2002, 52 (02) : 79 - 87
  • [47] Synthesis of a new β-naphthothiazole monomethine cyanine dye for the detection of DNA in aqueous solution
    El-Shishtawy, Reda M.
    Asiri, Abdullah M.
    Basaif, Salem A.
    Sobahi, T. Rashad
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2010, 75 (05) : 1605 - 1609
  • [48] SPECTRAL PROPERTIES OF TRIPLET STATES OF CYANINE AND THIAZINE DYES
    CHIBISOV, AK
    KUZMIN, VA
    ROITMAN, GP
    LEVKOEV, II
    KARYAKIN, AV
    IZVESTIYA AKADEMII NAUK SSSR SERIYA FIZICHESKAYA, 1970, 34 (06): : 1288 - &
  • [49] PREPARATION OF SOME NEW TRINUCLEAR CYANINE DYES
    FICKEN, GE
    FRY, DJ
    INDUSTRIE CHIMIQUE BELGE-BELGISCHE CHEMISCHE INDUSTRIE, 1966, 31 (SEP): : P140 - &
  • [50] Synthesis and properties of some naphtho (quinolino)-quinone heterocyclic dimethine cyanine dyes
    Dyes Pigm, 2 (89):
12345