Kinetic resolution of racemic epoxides using a chiral diamine catalyst

被引：7
|
作者：
Gayet, A [1 ]
Andersson, PG [1 ]
机构：
[1] Uppsala Univ, Dept Organ Chem, S-75124 Uppsala, Sweden
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 28期
关键词：
kinetic resolution; epoxide rearrangement; allylic alcohol; chiral diamine;
D O I：
10.1016/j.tetlet.2005.05.017
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The kinetic resolution of a variety of racemic epoxides has been performed using a chiral bicyclic diamine ligand. Using 5 mol% of catalyst very high selectivity could be achieved; both epoxide and the corresponding allylic alcohol could be obtained in up to 99% ee. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4805 / 4807
页数：3
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