Discovery of a novel and potent, and urea isostere inhibitors series of dianilinopyrimidineurea of VEGFR2 tyrosine kinase

被引：33

作者：

Sammond, DM ^{[1
]}

Nallor, KE ^{[1
]}

Veal, JM ^{[1
]}

Nolte, RT ^{[1
]}

Wang, LP ^{[1
]}

Knick, VB ^{[1
]}

Rudolph, SK ^{[1
]}

Truesdale, AT ^{[1
]}

Nartey, EN ^{[1
]}

Stafford, JA ^{[1
]}

Kumar, R ^{[1
]}

Cheung, M ^{[1
]}

机构：

[1] GlaxoSmithKline, Res Triangle Pk, NC 27709 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 15期

关键词：

VEGFR2; FLK-1; KDR; kinase inhibitor;

D O I：

10.1016/j.bmcl.2005.05.096

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：3519 / 3523

页数：5

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