Evaluation of serum sandwich enzyme-linked immunosorbent assay for circulating galactomannan during caspofungin therapy: Results from the caspofungin invasive aspergillosis study

被引：50

作者：

Maertens, J

Glasmacher, A

Selleslag, D

Ngai, A

Ryan, D

Layton, M

Taylor, A

Sable, C

Kartsonis, N

机构：

[1] Merck & Co Inc, Merck Res Labs, West Point, PA 19486 USA

[2] Univ Bonn, D-5300 Bonn, Germany

[3] Acad Hosp St Jan, Brugge, Belgium

[4] Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 41卷 / 01期

关键词：

D O I：

10.1086/430826

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There has been minimal clinical experience with the use of the Aspergillus galactomannan enzyme-linked immunosorbent assay (ELISA) for patients receiving echinocandin therapy. We reviewed the experience with the galactomannan ELISA for 17 patients in a study of caspofungin treatment for invasive aspergillosis. The rate of successful outcomes for these patients was similar to that overall for participants in the study. Trends in antigenemia levels correlated with clinical and radiographic findings.

引用

页码：E9 / E14

页数：6

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