Synthesis of nitrogen-containing spiro compounds from lactams by allylboration and subsequent ring-closing metathesis

被引：25

作者：

Nieczypor, P

Mol, JC

Bespalova, NB

Bubnov, YN

机构：

[1] Univ Amsterdam, Fac Sci, Inst Mol Chem, NL-1018 WV Amsterdam, Netherlands

[2] Russian Acad Sci, AV Topchiev Petrochem Synth Inst, Moscow 119991, Russia

[3] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 117991, Russia

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 2004卷 / 04期

关键词：

lactams; boron; nitrogen heterocycles; ring-closing metathesis; spiro compounds;

D O I：

10.1002/ejoc.200300373

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of nitrogen- containing spiro[4]alkenes was prepared with excellent yields starting from lactams in two steps: allylboration on the carbonyl carbon and subsequent ring-closing metathesis of the 2,2-diallyl N-heterocycles. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

引用

页码：812 / 819

页数：8

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