Interleukin-2-inducible T-cell Kinase (ITK) Targeting by BMS-509744 Does Not Affect Cell Viability in T-cell Prolymphocytic Leukemia (T-PLL)

被引：8
|
作者：
Dondorf, Sabine
Schrader, Alexandra [1 ]
Herling, Marco
机构：
[1] Univ Cologne, Lab Lymphocyte Signaling & Oncoproteome, Dept Internal Med 1, Ctr Integrated Oncol CIO Koln Bonn, D-50931 Cologne, Germany
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2015年 / 290卷 / 16期
关键词：
INHIBITORS;
D O I：
10.1074/jbc.L115.644641
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
6
引用
收藏
页码：10568 / 10569
页数：2
相关论文
共 50 条
  • [21] Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors
    Han, Seungil
    Czerwinski, Robert M.
    Caspers, Nicole L.
    Limburg, David C.
    Ding, WeiDong
    Wang, Hong
    Ohren, Jeffrey F.
    Rajamohan, Francis
    McLellan, Thomas J.
    Unwalla, Ray
    Choi, Chulho
    Parikh, Mihir D.
    Seth, Nilufer
    Edmonds, Jason
    Phillips, Chris
    Shakya, Subarna
    Li, Xin
    Spaulding, Vikki
    Hughes, Samantha
    Cook, Andrew
    Robinson, Colin
    Mathias, John P.
    Navratilova, Iva
    Medley, Quintus G.
    Anderson, David R.
    Kurumbail, Ravi G.
    Aulabaugh, Ann
    BIOCHEMICAL JOURNAL, 2014, 460 : 211 - 222
  • [22] Therapeutic Targeting of Interleukin-2-Inducible T-Cell Kinase (ITK) for Cancer and Immunological Disorders: Potential Next-Generation ITK Inhibitors
    Ahmed, Shazia
    Saeed, Mohammad Umar
    Choudhury, Arunabh
    Mohammad, Taj
    Hussain, Afzal
    Alajmi, Mohamed F.
    Yadav, Dharmendra Kumar
    Hassan, Md Imtaiyaz
    OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 2025, 29 (03) : 105 - 115
  • [23] Topical Application of BMS-509744, a Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase, Ameliorates Imiquimod-Induced Skin Inflammation in Mice
    Otake, Sho
    Otsubaki, Tomoko
    Uesato, Naofumi
    Ueda, Yoshifumi
    Murayama, Toshihiko
    Hayashi, Mikio
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2021, 44 (04) : 528 - 534
  • [24] Interleukin-2-inducible T-cell kinase inhibitors modify functional polarization of human peripheral T-cell lymphoma cells
    Mamand, Sami
    Carr, Matthew
    Allchin, Rebecca L.
    Ahearne, Matthew J.
    Wagner, Simon D.
    BLOOD ADVANCES, 2019, 3 (05) : 705 - 710
  • [25] T-cell receptor γδ T-cell leukemia with the morphology of T-cell prolymphocytic leukemia and a postthymic immunophenotype
    Sugimoto, T
    Imoto, S
    Matsuo, Y
    Kojima, K
    Yasukawa, M
    Murayama, T
    Kohfuku, J
    Mizuno, I
    Yakushijin, K
    Sada, A
    Nishimura, R
    Koizumi, T
    ANNALS OF HEMATOLOGY, 2001, 80 (12) : 749 - 751
  • [26] T-cell receptor γδ T-cell leukemia with the morphology of T-cell prolymphocytic leukemia and a postthymic immunophenotype
    T. Sugimoto
    S. Imoto
    Y. Matsuo
    K. Kojima
    M. Yasukawa
    T. Murayama
    J. Kohfuku
    I. Mizuno
    K. Yakushijin
    A. Sada
    R. Nishimura
    T. Koizumi
    Annals of Hematology, 2001, 80 : 749 - 751
  • [27] T-cell prolymphocytic leukemia
    Khot, Amit
    Dearden, Claire
    EXPERT REVIEW OF ANTICANCER THERAPY, 2009, 9 (03) : 365 - 371
  • [28] T-cell prolymphocytic leukemia
    Claire E. Dearden
    Medical Oncology, 2006, 23 : 17 - 22
  • [29] T-cell Prolymphocytic Leukemia
    Sud, Amit
    Dearden, Claire
    HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 2017, 31 (02) : 273 - +
  • [30] T-Cell Prolymphocytic Leukemia
    Dearden, Claire E.
    CLINICAL LYMPHOMA & MYELOMA, 2009, 9 : S239 - S243
12345