Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones

被引：0

作者：

Desai, N. C. ^{[1
]}

Bhatt, Nayan ^{[1
]}

Kumar, Mukesh ^{[1
]}

Makwana, Atul ^{[1
]}

机构：

[1] Bhavnagar Univ, Univ Dept Chem, Div Med Chem, Bhavnagar 364002, Gujarat, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 07期

关键词：

2-Aminobenzoic acid; benzene-1,2-diamine; benzimidazole; thiazolidinone; antibacterial activity; antifungal activity; BIOLOGICAL-ACTIVITY; DERIVATIVES; BENZIMIDAZOLES; METABOLITES; AGENTS; DRUG;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

As a part of systematic investigation of synthesis, characterization and biological activities, several new 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-I, have been synthesized from Schiff bases of benzimidazoles 2a-I, which have been predared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzenc-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus.

引用

页码：941 / 945

页数：5

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