Synthesis of Substituted 1,3-Oxazines Using Sulfamic Acid as an Efficient and Eco-Friendly Catalyst

被引：4

作者：

Damodiran, M. ^{[1
]}

Perumal, Paramasivan T. ^{[1
]}

机构：

[1] Cent Leather Res Inst, Div Organ Chem, Chennai 600020, Tamil Nadu, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2010年 / 47卷 / 06期

关键词：

ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; 3-COMPONENT SYNTHESIS; DOMINO REACTIONS; DERIVATIVES; MINIMYCIN; LIBRARIES;

D O I：

10.1002/jhet.489

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfamic acid catalyzed the synthesis of substituted 1,3-oxazines by one-pot three-component reaction of aniline, alkynoates, and formaldehyde in excellent yields. The catalyst possesses distinct advantages shows ease of handling, good yields, cleaner reactions, nonhygroscopic, noncorrosive, and high activity. Sulfamic acid is a green alternative for metal-containing acidic materials, which are toxic and deleterious for human health and environmental protection.

引用

页码：1386 / 1391

页数：6

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