共 50 条
- [31] 2-amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivoBRITISH JOURNAL OF PHARMACOLOGY, 1996, 119 (06) : 1101 - 1108Faraci, WSNagel, AAVerdries, KAVincent, LAXu, HNichols, LELabasi, JMSalter, EDPettipher, ER
- [32] Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivoBIOORGANIC & MEDICINAL CHEMISTRY, 2020, 28 (16)Tian, NannanWu, HuanxianZhang, HuiwuYang, DanniLv, LinYang, ZichaoZhang, TingtingQuan, DonglingZhou, LeiXie, YingXu, YimeiWei, NingZhang, JiajieChen, MianSchmitz, John C.Tian, YuanxinShaoyu, Wu
- [33] A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral ActivityJOURNAL OF VIROLOGY, 2017, 91 (11)Chong, HuihuiXue, JingXiong, ShengwenCong, ZheDing, XiaohuiZhu, YuanmeiLiu, ZixuanChen, TingFeng, YifanHe, LeiGuo, YanWei, QiangZhou, YusenQin, ChuanHe, Yuxian
- [34] The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivoEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 187Cui, Ying-JieMa, Chen-ChenZhang, Cheng-MeiTang, Long-QianLiu, Zhao-Peng
- [35] IMGN289, an EGFR-targeting antibody-maytansinoid conjugate with potent activity against non-small cell lung cancer (NSCLC) regardless of dependency on EGFR pathway.CANCER RESEARCH, 2013, 73 (08)Chittenden, Thomas D.Setiady, Yulius Y.Park, Peter U.Ponte, Jose F.Dong, LingSkaletskaya, AnnaCarrigan, Christina N.Villaluz, Alfred A.Pinkas, JanLutz, Robert J.Lambert, John M.
- [36] Remarkable In Vitro and In Vivo Activity of IMGN853, an Antibody-Drug Conjugate Targeting Folate Receptor Alpha Linked to the Tubulin-Disrupting Maytansinoid DM4, in Biologically Aggressive (Type II) Endometrial Cancers.REPRODUCTIVE SCIENCES, 2018, 25 : 90A - 91AAltwerger, GaryBonazzoli, ElenaBellone, StefaniaEgawa-Takata, TomomiMenderes, GuldenPettinella, FrancescaRiccio, FrancescoFeinberg, JacquelineZammataro, LucaHan, ChanheeYadav, GhanshyamDugan, KatherineMorneault, AshleyPonte, Jose F.Buza, NataliaHui, PeiWong, SerenaLitkouhi, BabakRatner, ElenaSilasi, Dan-ArinHuang, Gloria S.Azodi, MasoudSchwartz, Peter E.Santin, Alessandro D.
- [37] In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinomaGYNECOLOGIC ONCOLOGY, 2020, 156 (02) : 430 - 438Han, ChanheePerrone, EmanueleZeybek, BurakBellone, StefaniaTymon-Rosario, JoanAltwerger, GaryMenderes, GuldenFeinberg, JacquelineHaines, KaitlinKarger, Mariana Espinal MullerBianchi, AnnaZammataro, LucaManzano, AranzazuBonazzoli, ElenaManara, PaolaBuza, NataliaHui, PeiRatner, ElenaSilasi, Dan-ArinHuang, Gloria S.Azodi, MasoudSchwartz, Peter E.Lopez, SalvatoreSantin, Alessandro D.
- [38] In Vitro and In Vivo Antiviral Activity of Gingerenone A on Influenza A Virus Is Mediated by Targeting Janus Kinase 2VIRUSES-BASEL, 2020, 12 (10):Wang, JiongjiongPrinz, Richard A.Liu, XiufanXu, Xiulong
- [39] In Vitro and in vivo activity of ARRY-380: A potent, small molecule inhibitor of ErbB2.CANCER RESEARCH, 2009, 69Pheneger, TracyBouhana, KarynAnderson, DeborahGarrus, JenniferAhrendt, KateriAllen, ShelleyVon Carlowitz, IraGreschuk, JulieGross, StefanHoffman, KeithLemieux, ChristineLyssikatos, JoeCallejo, MicheleTarlton, GeneWallace, EliWinski, ShannonWoessner, RichZhao, QianMarmsater, FredLee, Patrice
- [40] Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of ActionCANCERS, 2020, 12 (12) : 1 - 16Wang, WeiWang, XinjieRajaei, MehrdadYoun, Ji YounZafar, AtifDeokar, HemantkumarBuolamwini, John K.Yang, JianhuaFoster, Jennifer H.Zhou, JiaZhang, Ruiwen