Biomineralization of Superhydrophilic Vertically Aligned Carbon Nanotubes

被引：24

作者：

Marsi, Teresa Cristina O. ^{[1
]}

Santos, Tiago G. ^{[1
]}

Pacheco-Soares, Cristina ^{[2
]}

Corat, Evaldo J. ^{[3
]}

Marciano, Fernanda R. ^{[1
]}

Lobo, Anderson O. ^{[1
]}

机构：

[1] Univ Vale Paraiba Univap, Dev Res Inst IP&D, Lab Biomed Nanotechnol, BR-12244000 Sao Jose Dos Campos, SP, Brazil

[2] Univ Vale Paraiba Univap, Dev Res Inst IP&D, Lab Cellular & Tissue Biol, BR-12244000 Sao Jose Dos Campos, SP, Brazil

[3] Natl Inst Space Res INPE, Associated Lab Sensors & Mat LAS, BR-12227010 Sao Jose Dos Campos, SP, Brazil

来源：

LANGMUIR | 2012年 / 28卷 / 09期

基金：

巴西圣保罗研究基金会;

关键词：

SIMULATED BODY-FLUID; BIOMIMETIC SYNTHESIS; CALCIUM PHOSPHATES; APATITE FORMATION; OXYGEN PLASMA; GROWTH; FILMS; HYDROXYAPATITE; SURFACES; CELLS;

D O I：

10.1021/la300111k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Vertically aligned carbon nanotubes (VACNT) promise a great role for the study of tissue regeneration. In this paper, we introduce a new biomimetic mineralization routine employing superhydrophilic VACNT films as highly stable template materials. The biomineralization was obtained after VACNT soaking in simulated body fluid solution. Detailed structural analysis reveals that the polycrystalline biological apatites formed due to the -COOH terminations attached to VACNT tips after oxygen plasma etching. Our approach not only provides a novel route for nanostructured materials, but also suggests that COOH termination sites can play a significant role in biomimetic mineralization. These new nanocomposites are very promising as nanobiomaterials due to the excellent human osteoblast adhesion.

引用

页码：4413 / 4424

页数：12

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