Base Pair Openings and Temperature Dependence of DNA Flexibility

被引：26
|
作者：
Theodorakopoulos, Nikos [1 ,2 ,3 ]
Peyrard, Michel [3 ]
机构：
[1] Natl Hellen Res Fdn, Inst Theoret & Phys Chem, GR-11635 Athens, Greece
[2] Univ Konstanz, Fachbereich Phys, D-78457 Constance, Germany
[3] Ecole Normale Super Lyon, Lab Phys CNRS, F-69364 Lyon 7, France
来源：
PHYSICAL REVIEW LETTERS | 2012年 / 108卷 / 07期
关键词：
PERSISTENCE LENGTH; MOLECULAR-WEIGHT; IMINO PROTON; DOUBLE HELIX; DENATURATION; EXCHANGE; BIREFRINGENCE; CYCLIZATION; FRAGMENTS; ACIDS;
D O I：
10.1103/PhysRevLett.108.078104
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
The relationship of base pair openings to DNA flexibility is examined. Published experimental data on the temperature dependence of the persistence length by two different groups are well described in terms of an inhomogeneous Kratky-Porot model with soft and hard joints, corresponding to open and closed base pairs, and sequence-dependent statistical information about the state of each pair provided by a Peyrard-Bishop-Dauxois (PBD) model calculation with no freely adjustable parameters.
引用
收藏
页数：4
相关论文
共 50 条
  • [1] MOLECULAR MECHANICAL STUDIES OF DNA FLEXIBILITY - COUPLED BACKBONE TORSION ANGLES AND BASE-PAIR OPENINGS
    KEEPERS, JW
    KOLLMAN, PA
    WEINER, PK
    JAMES, TL
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (18): : 5537 - 5541
  • [2] DEPENDENCE OF DNA HELIX FLEXIBILITY ON BASE COMPOSITION
    HOGAN, M
    LEGRANGE, J
    AUSTIN, B
    NATURE, 1983, 304 (5928) : 752 - 754
  • [3] Correlated motions in DNA: beyond base-pair step models of DNA flexibility
    Lopez-Guell, Kim
    Battistini, Federica
    Orozco, Modesto
    NUCLEIC ACIDS RESEARCH, 2023, 51 (06) : 2633 - 2640
  • [4] DNA Flexibility does not show Appreciable Temperature Dependence
    Kayikcioglu, Tunc
    Ha, Taekjip
    BIOPHYSICAL JOURNAL, 2016, 110 (03) : 403A - 403A
  • [5] Single-molecule DNA flexibility in the presence of base-pair mismatch
    Schallhorn, KA
    Freedman, KO
    Moore, JM
    Lin, J
    Ke, PC
    APPLIED PHYSICS LETTERS, 2005, 87 (03)
  • [6] BETAINE CAN ELIMINATE THE BASE PAIR COMPOSITION DEPENDENCE OF DNA MELTING
    REES, WA
    YAGER, TD
    KORTE, J
    VONHIPPEL, PH
    BIOCHEMISTRY, 1993, 32 (01) : 137 - 144
  • [7] DEPENDENCE OF THE MUTAGENIC POWER OF HETEROATOMIC DYES ON THEIR DNA-BASE-PAIR SPECIFICITY
    MENNIGMANN, HD
    MULLER, W
    MUTATION RESEARCH, 1981, 91 (03): : 183 - 191
  • [8] TEMPERATURE-DEPENDENCE OF ACID-BASE-EQUILIBRIUM IN DNA
    SLONITSKII, SV
    KUPTSOV, VY
    MOLECULAR BIOLOGY, 1994, 28 (02) : 318 - 320
  • [9] DNA base pairs openings perturbed by the surrounding medium
    Saha, Mirabeau
    Kofane, Timoleon C.
    COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION, 2015, 23 (1-3) : 1 - 9
  • [10] The Effects of Base Stacking on DNA Flexibility
    Mogil, Lauren S.
    Peters, Justin P.
    Maher, Jim
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 274A - 274A
12345