Current Radiotherapy Considerations for Nasopharyngeal Carcinoma

被引:26
|
作者
Ng, Wai Tong [1 ,2 ,3 ]
Chow, James C. H. [4 ]
Beitler, Jonathan J. [5 ]
Corry, June [6 ]
Mendenhall, William [7 ]
Lee, Anne W. M. [1 ,2 ]
Robbins, K. Thomas [8 ]
Nuyts, Sandra [9 ]
Saba, Nabil F. [10 ]
Smee, Robert [11 ]
Stokes, William A. [12 ]
Strojan, Primoz [13 ]
Ferlito, Alfio
机构
[1] Univ Hong Kong, Shenzhen Hosp, Clin Oncol Ctr, Shenzhen 518009, Peoples R China
[2] Univ Hong Kong, Shenzhen Hosp, Shenzhen Key Lab Canc Metastasis & Personalized Th, Shenzhen 518009, Peoples R China
[3] Univ Hong Kong, Li Ka Shing Fac Med, Dept Clin Oncol, Hong Kong, Peoples R China
[4] Queen Elizabeth Hosp, Dept Clin Oncol, Hong Kong, Peoples R China
[5] Knox Cty Hlth Clin, Rockland, ME 04841 USA
[6] St Vincents Hosp, Div Radiat Oncol, GenesisCare Radiat Oncol, Melbourne, Vic 3065, Australia
[7] Univ Florida, Dept Radiat Oncol, Coll Med, Gainesville, FL 32610 USA
[8] Southern Illinois Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Springfield, IL 62794 USA
[9] Univ Leuven, KU Leuven, Univ Hosp Leuven, Dept Radiat Oncol, B-3000 Leuven, Belgium
[10] Emory Univ, Winship Canc Inst, Dept Hematol & Med Oncol, Sch Med, Atlanta, GA 30322 USA
[11] Prince Wales Canc Ctr, Dept Radiat Oncol, Sydney, NSW 2031, Australia
[12] Emory Univ, Winship Canc Inst, Dept Radiat Oncol, Sch Med, Atlanta, GA 30322 USA
[13] Inst Oncol, Dept Radiat Oncol, Ljubljana 1000, Slovenia
关键词
nasopharyngeal cancer; radiotherapy; target delineation; adaptive planning; artificial intelligence; particle therapy; INTENSITY-MODULATED RADIOTHERAPY; CLINICAL TARGET VOLUME; LYMPH-NODE DISTRIBUTION; QUALITY-OF-LIFE; RADIATION-THERAPY; ARTIFICIAL-INTELLIGENCE; INDUCTION CHEMOTHERAPY; TREATMENT OUTCOMES; PROTON THERAPY; NCIC CTG;
D O I
10.3390/cancers14235773
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Simple Summary Nasopharyngeal carcinoma (NPC) is commonly treated using high-dose radiotherapy. Careful radiotherapy planning is crucial for the eradication of cancer cells while avoiding injuries to normal structures. This balance is often delicate given the complex anatomic location in which NPC is situated. This article highlights the considerations, practical pearls, and recent advances in the precise delivery of radiotherapy in NPC patients. Radiotherapy is the primary treatment modality for nasopharyngeal carcinoma (NPC). Successful curative treatment requires optimal radiotherapy planning and precise beam delivery that maximizes locoregional control while minimizing treatment-related side effects. In this article, we highlight considerations in target delineation, radiation dose, and the adoption of technological advances with the aim of optimizing the benefits of radiotherapy in NPC patients.
引用
收藏
页数:15
相关论文
共 50 条
  • [21] Etiology and management of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma
    Zhan, Jiabin
    Zhang, Shuai
    Wei, Xin
    Fu, Yihui
    Zheng, Jing
    CANCER MANAGEMENT AND RESEARCH, 2019, 11 : 2171 - 2178
  • [22] Current Perspectives on Nasopharyngeal Carcinoma
    Lee, Hui Mei
    Okuda, Kazuhida Shaun
    Gonzalez, Fermin E.
    Patel, Vyomesh
    HUMAN CELL TRANSFORMATION: ADVANCES IN CELL MODELS FOR THE STUDY OF CANCER AND AGING, 2019, 1164 : 11 - 34
  • [23] Current state, challenges, and future perspective of adaptive radiotherapy: A narrative review of nasopharyngeal carcinoma
    Zhou, Xiate
    Shao, Tianchi
    Jia, Haijian
    Hou, Liqiao
    Tang, Xingni
    Yu, Changhui
    Zhou, Chao
    Zhou, Suna
    Yang, Haihua
    ORAL ONCOLOGY, 2024, 158
  • [24] Current treatment of nasopharyngeal carcinoma
    Chan, Anthony T. C.
    EUROPEAN JOURNAL OF CANCER, 2011, 47 : S302 - S303
  • [25] Proton versus photon radiotherapy for hepatocellular carcinoma: Current data and technical considerations
    Roberts, Hannah J.
    Hong, Theodore S.
    JOURNAL OF RADIOSURGERY AND SBRT, 2023, 9 (01): : 9 - 16
  • [26] Thyroid toxicity after radiotherapy of nasopharyngeal carcinoma
    Siala, W.
    Mnejja, W.
    Abid, M.
    Ghorbel, A.
    Frikha, M.
    Daoud, J.
    ANNALES D ENDOCRINOLOGIE, 2011, 72 (01) : 19 - 23
  • [27] Management of hypothyroidism after radiotherapy for nasopharyngeal carcinoma
    David H. Garfield
    Aleck Hercbergs
    Paul Davis
    Medical Oncology, 2008, 25 : 474 - 475
  • [28] SYNCHRONOUS RADIOTHERAPY AND CHEMOTHERAPY IN THE TREATMENT OF NASOPHARYNGEAL CARCINOMA
    TURNER, SL
    TIVER, KW
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 27 (02): : 371 - 377
  • [29] RADICAL RADIOTHERAPY IN ELDERLY PATIENTS WITH NASOPHARYNGEAL CARCINOMA
    Sze, H.
    Ng, W. T.
    Yau, T. K.
    Lee, A.
    RADIOTHERAPY AND ONCOLOGY, 2010, 96 : S328 - S328
  • [30] Cochlea sparing optimized radiotherapy for nasopharyngeal carcinoma
    Enkelejda Lamaj
    Erwin Vu
    Janita E. van Timmeren
    Chiara Leonardi
    Louise Marc
    Izabela Pytko
    Matthias Guckenberger
    Panagiotis Balermpas
    Radiation Oncology, 16