Long-Term Safety in a Phase 1 Study of Siltuximab (CNTO 328), an Anti-Interleukin-6 Monoclonal Antibody, in Patients with B-Cell Non-Hodgkin's Lymphoma, Multiple Myeloma, or Castleman's Disease

被引:2
|
作者
Kurzrock, Razelle [1 ]
Voorhees, Peter M. [2 ]
Casper, Corey [3 ]
Furman, Richard R. [4 ]
Fayad, Luis [1 ]
Lonial, Sagar [5 ]
Borghaei, Hossein [6 ]
Jagannath, Sundar [7 ]
Sokol, Lubomir [8 ]
Usmani, Saad [9 ]
van de Velde, Helgi [10 ]
Qin, Xiang [11 ]
Qi, Ming [11 ]
Cornfeld, Mark J. [12 ]
van Rhee, Frits [13 ]
机构
[1] Univ Texas Houston, MD Anderson Canc Ctr, Houston, TX 77030 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
[3] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
[4] Cornell Univ, Weill Med Coll, New York, NY 10021 USA
[5] Emory Univ, Sch Med, Winship Canc Inst, Atlanta, GA USA
[6] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA
[7] St Vincents Comprehens Canc Ctr, New York, NY USA
[8] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33682 USA
[9] Univ Arkansas Med Sci, Myeloma Inst Res & Therapy, Little Rock, AR 72205 USA
[10] Janssen Res & Dev, Beerse, Belgium
[11] Ortho Biotech Oncol Res & Dev, Malvern, PA USA
[12] Ortho Biotech Oncol Res & Dev, Raritan, NJ USA
[13] Bon Secours St Francis Hlth Syst, Hematol Oncol, Greenville, SC USA
关键词
D O I
10.1182/blood.V118.21.3959.3959
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
下载
收藏
页码:1693 / 1693
页数:1
相关论文
共 50 条
  • [21] Rituximab long-term maintenance therapy after autologous stem cell transplantation in patients with B-cell non-Hodgkin’s lymphoma
    Frank Neumann
    Stefani Harmsen
    Simona Martin
    Ralf Kronenwett
    Mustafa Kondakci
    Manuel Aivado
    Ulrich Germing
    Rainer Haas
    Guido Kobbe
    Annals of Hematology, 2006, 85 : 530 - 534
  • [22] Long-Term Results from a Phase 1b Study of Avadomide in Combination with Obinutuzumab in Patients with Relapsed and/or Refractory B-Cell Non-Hodgkin Lymphoma
    Michot, Jean-Marie
    Bouabdallah, Reda
    Doorduijn, Jeanette K.
    Boccomini, Carola
    Kersten, Marie Jose
    Chiappella, Annalisa
    Zinzani, Pier Luigi
    Salles, Gilles
    Bijou, Fontanet
    Hentrup, Mei
    Rhee, So Hyun
    Hagner, Patrick
    Klein, Christian
    Pourdehnad, Michael
    Hege, Kristen
    Dobmeyer, Juergen
    Nikolova, Zariana
    Ribrag, Vincent
    BLOOD, 2020, 136
  • [23] A Phase I Study of Ibrutinib and Lenalidomide in Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma
    Christian, Beth
    Kuruvilla, John
    Smith, Sonali
    Porcu, Pierluigi
    Ruppert, Amy S.
    Byrd, John C.
    Grever, Michael R.
    Blum, Kristie A.
    BLOOD, 2014, 124 (21)
  • [24] Phase I clinical study of atacicept in patients with relapsed and refractory B-cell non-Hodgkin's lymphoma
    Ansell, Stephen M.
    Witzig, Thomas E.
    Inwards, David J.
    Porrata, Luis F.
    Ythier, Arnaud
    Ferrande, Lee
    Nestorov, Ivan
    Devries, Todd
    Dillon, Stacey R.
    Hausman, Diana
    Novak, Anne J.
    CLINICAL CANCER RESEARCH, 2008, 14 (04) : 1105 - 1110
  • [25] Combination immunotherapy of B-cell non-Hodgkin's lymphoma with rituximab and interleukin-2: A preclinical and phase I study
    Eisenbeis, CF
    Grainger, A
    Fischer, B
    Baiocchi, RA
    Carrodeguas, L
    Roychowdhury, S
    Chen, L
    Banks, AL
    Davis, T
    Young, D
    Kelbick, N
    Stephens, J
    Byrd, JC
    Grever, MR
    Caligiuri, MA
    Porcu, P
    CLINICAL CANCER RESEARCH, 2004, 10 (18) : 6101 - 6110
  • [26] Treatment of patients with mantle cell and aggressive B-cell non-Hodgkin's lymphoma using the monoclonal anti-CD20 antibody rituximab (Rituxan™):: Evaluation of safety and response.
    Winkler, U
    Schulz, HR
    Klein, TO
    Jensen, M
    Manzke, O
    Schmitz, SH
    Rüdiger, T
    Müller-Hermelink, KH
    Diehl, V
    Engert, A
    BLOOD, 1999, 94 (10) : 270B - 270B
  • [27] Tri-lineage disease involving sideroblastic anaemia, multiple myeloma and B-cell non-Hodgkin’s lymphoma in the same patient
    Jean-Christophe Ianotto
    Adrian Tempescul
    Jean-Richard Eveillard
    Véronique Marion
    Isabelle Quintin-Roué
    Christian Berthou
    Annals of Hematology, 2009, 88 : 273 - 274
  • [28] Tri-lineage disease involving sideroblastic anaemia, multiple myeloma and B-cell non-Hodgkin's lymphoma in the same patient
    Ianotto, Jean-Christophe
    Tempescul, Adrian
    Eveillard, Jean-Richard
    Marion, Veronique
    Quintin-Roue, Isabelle
    Berthou, Christian
    ANNALS OF HEMATOLOGY, 2009, 88 (03) : 273 - 274
  • [29] Phase II study of oblimersen sodium and rituximab in patients with recurrent B-cell non-Hodgkin's lymphoma.
    Pro, B
    Smith, MR
    Leber, B
    Younes, A
    Fayad, L
    Hagemeister, FB
    McLaughlin, P
    Rodriguez, AM
    Caddick, Y
    Zwiebel, JA
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 587S - 587S
  • [30] Phase 1 Study Evaluating Pharmacokinetics and Tolerability of Ofatumumab Combined With Bendamustine in Patients With Indolent B-Cell Non-Hodgkin's Lymphoma
    Forero-Torres, Andres
    Chandler, Jason Claud
    Iyer, Swaminathan P.
    Kanate, Abraham S.
    Quinlan, Michelle
    Hoever, Petra
    Izquierdo, Miguel
    Davis, Jaclyn
    Madan, Sumit
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2022, 11 (09): : 1099 - 1109