Impact of human sequences in variable domains of therapeutic antibodies on the location of CD4 T-cell epitopes

被引:14
|
作者
Meunier, Sylvain [1 ]
Hamze, Moustafa [1 ]
Karle, Anette [2 ]
de Bourayne, Marie [1 ]
Gdoura, Abdelaziz [1 ]
Spindeldreher, Sebastian [2 ,3 ]
Maillere, Bernard [1 ]
机构
[1] Univ Paris Saclay, Inst Freder Joliot, SIMOPRO, CEA Saclay, F-91191 Gif Sur Yvette, France
[2] Novartis Pharma AG, Basel, Switzerland
[3] Integrated Biologix GmbH, Basel, Switzerland
关键词
D O I
10.1038/s41423-019-0304-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:656 / 658
页数:3
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