Carbon-Carbon Bond Formation via Catalytically Generated Aminocarbene Complexes: Rhodium-Catalyzed Hydroaminative Cyclization of Enynes with Secondary Amines

被引：10

作者：

Takano, Shotaro ^{[1
]}

Shiomi, Ryosuke ^{[1
]}

Morimoto, Yoshihiko ^{[1
]}

Kochi, Takuya ^{[1
]}

Kakiuchi, Fumitoshi ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, 3-14-1 Hiyoshi, Yokohama, Kanagawa 2238522, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2020年 / 59卷 / 29期

关键词：

aminocarbene complexes; enynes; hydroaminative cyclization; rhodium; secondary amines; FISCHER CARBENE COMPLEXES; C-H ACTIVATION; CYCLOPROPANATION REACTIONS; INSERTION REACTIONS; CHROMIUM; CYCLOISOMERIZATION; REACTIVITY; ALKYNES; VINYLIDENE; CHEMISTRY;

D O I：

10.1002/anie.202002710

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a hydroaminative cyclization of enynes using phosphine-quinolinolato rhodium catalysts. The hydroaminative cyclization of 2-vinylphenylacetylene derivatives with secondary amines gives 2-aminoindenes in good yields. The reaction is considered to proceed through carbon-carbon bond formation on a catalytically generated aminocarbene ligand.

引用

页码：11754 / 11757

页数：4

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