In vitro interaction of posaconazole and caspofungin against clinical isolates of Candida glabrata

被引：25
|
作者：
Oliveira, ER
Fothergill, AW
Kirkpatrick, WR
Coco, BJ
Patterson, TF
Redding, SW
机构：
[1] Univ Texas, Hlth Sci Ctr, Dept Gen Dent, San Antonio, TX 78229 USA
[2] Univ Texas, Hlth Sci Ctr, Dept Pathol, San Antonio, TX 78229 USA
[3] Univ Texas, Hlth Sci Ctr, Dept Med, Div Infect Dis, San Antonio, TX 78229 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 08期
关键词：
D O I：
10.1128/AAC.49.8.3544-3545.2005
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Combinations of caspofungin and posaconazole were evaluated by fractional inhibitory concentration index against 119 Candida glabrata isolates. Synergy was seen in 18% of all isolates and in 4% of fluconazole-resistant isolates at 48 h without evidence of antagonism. This antifungal combination may have utility against this organism.
引用
收藏
页码：3544 / 3545
页数：2
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