Diuretics and tubuloglomerular feedback.

被引：0

作者：

Knauf, H ^{[1
]}

Greger, R ^{[1
]}

Mutschler, E ^{[1
]}

Paliege, R ^{[1
]}

Thurau, K ^{[1
]}

机构：

[1] ST BERNWARD KRANKENHAUS,MED KLIN 1,HILDESHEIM,GERMANY

来源：

NIEREN-UND HOCHDRUCKKRANKHEITEN | 1996年 / 25卷 / 04期

关键词：

tubuloglomerular feedback; loop diuretics; thiazides; antikaliuretics; renal hemodynamics;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The GFR is depressed by 40 to 50% once the natriuresis induced by thiazides exceeds 35 mmol/h. This effect is termed tubuloglomerular feedback (TGR). Loop diuretics do not affect the GFR and the RPF as they block the TGR. Therefore their effect is not limited by the reduction of GFR. Hence thiazides being self-limited were earlier called low ceiling diuretics and loop diuretics were called ''high ceiling'' diuretics.

引用

页码：147 / 153

页数：7

共 50 条

[1] DIURETICS AND TUBULOGLOMERULAR FEEDBACK
KNAUF, H
PALIEGE, R
MUTSCHLER, E
THURAU, K
INTERNIST, 1992, 33 : S10 - S15
[2] EFFECT OF DIURETICS ON THE TUBULOGLOMERULAR FEEDBACK RESPONSE
GUTSCHE, HU
BRUNKHORST, R
MULLEROTT, K
FRANKE, H
NIEDERMAYER, W
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1984, 62 (04) : 412 - 417
[3] THE EFFECT OF LOOP OF HENLE DIURETICS ON THE TUBULOGLOMERULAR FEEDBACK MECHANISM
JOHNSTON, PA
KAU, ST
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, 1992, 14 (07): : 523 - 529
[4] The role of nitric oxide synthase in macula densa in the resetting of tubuloglomerular feedback.
Kawata, T
Hashimoto, S
Murakami, K
Tsuchiya, K
Koike, T
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1996, 7 (09): : A1668 - A1668
[5] Potential natriuretic effects of limit-cycle oscillations mediated by tubuloglomerular feedback.
Layton, HE
Pitman, EB
Moore, LC
FASEB JOURNAL, 1998, 12 (04): : A108 - A108
[6] Internephron coupling may contribute to emergence of irregular oscillations mediated by tubuloglomerular feedback.
Layton, AT
Moore, LC
Layton, HE
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 : 333A - 333A
[7] Salt intake determines renal thromboxane receptor mRNA expression and function in tubuloglomerular feedback.
Welch, WJ
Peng, B
Wilcox, CS
FASEB JOURNAL, 1996, 10 (03): : 3147 - 3147
[8] Natriuretic response to A1 adenosine receptor blockade: Roles of proximal reabsorption and tubuloglomerular feedback.
Welch, WJ
Schreiner, GF
Belardinelli, L
Wilcox, CS
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1996, 7 (09): : A1469 - A1469
[9] Tubuloglomerular feedback
Castrop H.
Der Nephrologe, 2016, 11 (2): : 150 - 152
[10] TUBULOGLOMERULAR FEEDBACK
THOMSON, SC
BLANTZ, RC
AMERICAN JOURNAL OF NEPHROLOGY, 1988, 8 (05) : 393 - 401

← 1 2 3 4 5 →