What does the corpus callosum tell us about brain changes in the elderly?

被引：0

作者：

Di Paola, Margherita ^{[1
,2
]}

Caltagirone, Carlo ^{[1
,3
]}

Spalletta, Gianfranco ^{[1
]}

机构：

[1] IRCCS Santa Lucia Fdn, I-00179 Rome, Italy

[2] Univ Aquila, Dept Internal Med & Publ Hlth, I-67010 Laquila, Italy

[3] Univ Rome, Dept Neurosci & Memory Clin, I-00133 Rome, Italy

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2011年 / 11卷 / 11期

关键词：

age-related white matter changes; corpus callosum; demyelination process; diffusion tensor imaging; elderly; region of interest; Wallerian degeneration; ALZHEIMERS-DISEASE; ATROPHY; DEGENERATION; IMPAIRMENT; MRI;

D O I：

10.1586/ERN.11.130

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The corpus callosum is the largest hemispheric interconnection bundle in the human brain. Its anterior-posterior fiber caliber gradient can help in understanding the pathophysiological mechanisms underlying white matter changes both in old age and dementia. Here, the Leukoaraiosis and Disability (LADIS) study, a longitudinal cohort study, which shows an association between corpus callosum atrophy and cognitive and motor decline in the elderly, provides the possibility to consider the use of multimodal macro-microstructural imaging of corpus callosum as a marker of structural brain changes of physiological and pathological aging.

引用

页码：1557 / 1560

页数：4

共 50 条

[1] What does the brain tell us about the mind?
Ruz, Maria
Acero, Juan J.
Tudela, Pio
[J]. PSICOLOGICA, 2006, 27 (02): : 149 - 167
[2] What does the brain tell us about abstract art?
Aviv, Vered
[J]. FRONTIERS IN HUMAN NEUROSCIENCE, 2014, 8
[3] What does the developing brain tell us about neural diseases?
Stoeckli, Esther T.
[J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2012, 35 (12) : 1811 - 1817
[4] What does brain damage tell us about the mechanisms of sleep?
Evans, BM
[J]. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 2002, 95 (12) : 591 - 597
[5] What do studies ofthe corpus callosum in animals tell us about prenatal alcohol effects in humans?
Elberger, Andrea J.
[J]. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2007, 31 (06) : 250A - 250A
[6] What words tell us about the brain
Raichle, ME
[J]. BASIC MECHANISMS IN COGNITION AND LANGUAGE: WITH SPECIAL REFERENCE TO PHONOLOGICAL PROBLEMS IN DYSLEXIA, 1998, 70 : 87 - 99
[7] What does brain Imaging tell us about the predisposition to suicidal behavior
Mann, J. J.
[J]. CRISIS-THE JOURNAL OF CRISIS INTERVENTION AND SUICIDE PREVENTION, 2005, 26 (03) : 101 - 103
[8] Proteomic profiling of mitochondria: what does it tell us about the ageing brain?
Ingram, Thomas
Chakrabarti, Lisa
[J]. AGING-US, 2016, 8 (12): : 3161 - 3179
[9] Contralateral corpus luteum in ectopic pregnancy: What does it tell us about ovum pickup?
Ziel, HK
Paulson, RJ
[J]. FERTILITY AND STERILITY, 2002, 77 (04) : 850 - 851
[10] What Does the Sky Tell Us about the Camera?
Lalonde, Jean-Franqois
Narasimhan, Srinivasa G.
Efros, Alexei A.
[J]. COMPUTER VISION - ECCV 2008, PT IV, PROCEEDINGS, 2008, 5305 : 354 - +

← 1 2 3 4 5 →