STIM1 moonlights as an anchor for STING

被引：12
|
作者：
Wu, Jianjun [1 ]
Yan, Nan [1 ,2 ]
机构：
[1] Univ Texas Southwestern Med Ctr Dallas, Dept Immunol, Dallas, TX 75390 USA
[2] Univ Texas Southwestern Med Ctr Dallas, Dept Microbiol, Dallas, TX 75390 USA
来源：
NATURE IMMUNOLOGY | 2019年 / 20卷 / 02期
关键词：
TRAFFICKING; ACTIVATION; ER;
D O I：
10.1038/s41590-018-0300-2
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Activation of STING requires its translocation from the endoplasmic reticulum (ER) through the Golgi to vesicles, but the mechanisms that control its localization have been unclear. The ER calcium sensor STIM1 acts as an ER-retention factor that anchors STING on the ER and limits STING signaling.
引用
收藏
页码：112 / 114
页数：3
相关论文
共 50 条
  • [1] STIM1 moonlights as an anchor for STING
    Jianjun Wu
    Nan Yan
    Nature Immunology, 2019, 20 : 112 - 114
  • [2] STIM1 holds a STING in its (N-terminal) tail
    Son, Aran
    de Jesus, Adriana Almeida
    Schwartz, Daniella M.
    CELL CALCIUM, 2019, 80 : 192 - 193
  • [3] Role of the STIM1 C-terminal Domain in STIM1 Clustering
    Yu, Fang
    Sun, Lu
    Courjaret, Raphael
    Machaca, Khaled
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (10) : 8375 - 8384
  • [4] The STIM1 Phosphorylation Saga
    Yu, Fang
    Machaca, Khaled
    CELL CALCIUM, 2022, 103
  • [5] The STIM1: Orai Interaction
    Frischauf, Irene
    Fahrner, Marc
    Jardin, Isaac
    Romanin, Christoph
    CALCIUM ENTRY PATHWAYS IN NON-EXCITABLE CELLS, 2016, 898 : 25 - 46
  • [6] STIM1: The lord of the rings?
    Pacheco, Jonathan
    Sampieri, Alicia
    Vaca, Luis
    CELL CALCIUM, 2023, 112
  • [7] STIM1 is cleaved by calpain
    Prins, Daniel
    Michalak, Marek
    FEBS LETTERS, 2015, 589 (21) : 3294 - 3301
  • [8] POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters
    Krapivinsky, Grigory
    Krapivinsky, Luba
    Stotz, Stephanie C.
    Manasian, Yunona
    Clapham, David E.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (48) : 19234 - 19239
  • [9] ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
    Michael Chvanov
    Ciara M. Walsh
    Lee P. Haynes
    Svetlana G. Voronina
    Gyorgy Lur
    Oleg V. Gerasimenko
    Roger Barraclough
    Philip S. Rudland
    Ole H. Petersen
    Robert D. Burgoyne
    Alexei V. Tepikin
    Pflügers Archiv - European Journal of Physiology, 2008, 457 : 505 - 517
  • [10] STIM1 and the noncapacitative ARC channels
    Shuttleworth, Trevor J.
    Thompson, Jill L.
    Mignen, Olivier
    CELL CALCIUM, 2007, 42 (02) : 183 - 191
12345