ANTIBACTERIAL ACTIVITY OF PROPOLIS PRODUCED BY Frieseomelitta varia

被引:12
|
作者
Costa Campos, Viviane Aparecida [1 ]
dos Santos Junior, Helvecio Martins [1 ]
Oliveira, Denilson F. [1 ]
Pereira de Carvalho, Hudson Walace [1 ]
Teixeira Machado, Alan Rodrigues [1 ]
Tirelli, Aline Auxiliadora [1 ]
机构
[1] Univ Fed Lavras UFLA, Dept Quim DQI, Lab Prod Nat, BR-37200000 Lavras, MG, Brazil
来源
CIENCIA E AGROTECNOLOGIA | 2011年 / 35卷 / 06期
关键词
Artepillin C; stingless bees; antibiotic; BRAZILIAN PROPOLIS; PHYTOCHEMICAL EVIDENCE; CHEMICAL-CONSTITUENTS; PLANT-ORIGIN; SUSCEPTIBILITY; SOUTHEASTERN; ANTIOXIDANT; EXPRESSION;
D O I
10.1590/S1413-70542011000600002
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
To contribute to the development of antibacterial products from propolis produced by native Brazilian bees, twenty-nine samples of propolis collected from hives in the state of Minas Gerais, Brazil, were screened for in vitro activity against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. Among the samples from native Brazilian bees, only that from Frieseomelitta varia (Lepeletier, 1836) inhibited in vitro bacterial growth. Consequently, this propolis underwent fractionation by chromatographic methods monitored through Agar-diffusion assays with these bacteria, which resulted in the isolation and identification of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C), which showed MIC of 62.5 and 250 mu g/mL against B. subtilis and S. aureus, respectively. This result indicates the potential of F. varia to produce therapeutic propolis.
引用
收藏
页码:1043 / 1049
页数:7
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