Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia

被引：20
|
作者：
Veronese, L. [1 ,2 ]
Tournilhac, O. [3 ]
Verrelle, P. [2 ,4 ]
Davi, F. [5 ,6 ]
Dighiero, G. [7 ]
Chautard, E. [2 ]
Veyrat-Masson, R. [8 ]
Kwiatkowski, F. [9 ]
Goumy, C. [1 ]
Vago, P. [1 ]
Travade, P. [3 ]
Tchirkov, A. [1 ,2 ,4 ]
机构：
[1] Univ Clermont 1, CHU Clermont Ferrand, UFR Med, Serv Cytogenet Med, Clermont Ferrand, France
[2] Univ Auvergne, EA 3846, Clermont Ferrand, France
[3] CHU Clermont Ferrand, Serv Hematol Clin, Clermont Ferrand, France
[4] Ctr Jean Perrin, Dept Radiotherapie, Clermont Ferrand, France
[5] Serv Hematol Biol, Paris, France
[6] Univ Paris 06, Hop Pitie Salpetriere, Paris, France
[7] Inst Pasteur, Montevideo, Uruguay
[8] CHU Clermont Ferrand, Serv Hematol Biol, Clermont Ferrand, France
[9] Ctr Jean Perrin, Serv Stat & Commun Med, Clermont Ferrand, France
来源：
LEUKEMIA | 2008年 / 22卷 / 06期
关键词：
D O I：
10.1038/sj.leu.2405052
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：1291 / 1293
页数：3
相关论文
共 50 条
  • [21] Expression of MUM1 correlates with clinical outcomes in patients with B-cell chronic lymphocytic leukemia.
    Lorek, J
    Cleveland, R
    Kampalath, B
    Trzpuc, T
    Abed, N
    Chang, C
    BLOOD, 2001, 98 (11) : 357A - 358A
  • [22] MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells
    Bottardi, Stefania
    Guieze, Romain
    Bourgoin, Vincent
    Fotouhi-Ardakani, Nasser
    Douge, Aurore
    Darracq, Anais
    Lakehal, Yahia A.
    Berger, Marc G.
    Mollica, Luigina
    Bay, Jacques-Olivier
    Omichinski, James G.
    Milot, Eric
    EXPERIMENTAL HEMATOLOGY, 2020, 88 : 68 - +
  • [23] Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells
    Chen, Lisa S.
    Keating, Michael J.
    Wierda, William G.
    Gandhi, Varsha
    LEUKEMIA & LYMPHOMA, 2019, 60 (12) : 3063 - 3066
  • [24] The Akt/Mcl-1 pathway plays a prominent role in mediating pro-survival signals derived from the B-cell receptor in chronic lymphocytic leukemia B-cells
    Longo, Pablo G.
    Laurenti, Luca
    Gobessi, Stefania
    Sica, Simona
    Leone, Giuseppe
    Efremov, Dimitar G.
    BLOOD, 2007, 110 (11) : 107A - 107A
  • [25] Regulation of Mcl-1 Expression in Context to Bone Marrow Stromal Microenvironment in Chronic Lymphocytic Leukemia
    Balakrishnan, Kumudha
    Burger, Jan A.
    Fu, Min
    Doifode, Tejaswini
    Wierda, William G.
    Gandhi, Varsha
    NEOPLASIA, 2014, 16 (12): : 1036 - 1046
  • [26] c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells
    Allen, John C.
    Talab, Fatima
    Zuzel, Mirko
    Lin, Ke
    Slupsky, Joseph R.
    BLOOD, 2011, 117 (08) : 2414 - 2422
  • [27] Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab
    Awan, Farrukh T.
    Kay, Neil E.
    Davis, Melanie E.
    Wu, Wenting
    Geyer, Susan M.
    Leung, Nelson
    Jelinek, Diane F.
    Tschumper, Renee C.
    Secreto, Charla R.
    Lin, Thomas S.
    Grever, Michael R.
    Shanafelt, Tait D.
    Zent, Clive S.
    Call, Timothy G.
    Heerema, Nyla A.
    Lozanski, Gerard
    Byrd, John C.
    Lucas, David M.
    BLOOD, 2009, 113 (03) : 535 - 537
  • [28] The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression
    A D Baudot
    P Y Jeandel
    X Mouska
    U Maurer
    S Tartare-Deckert
    S D Raynaud
    J P Cassuto
    M Ticchioni
    M Deckert
    Oncogene, 2009, 28 : 3261 - 3273
  • [29] The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression
    Baudot, A. D.
    Jeandel, P. Y.
    Mouska, X.
    Maurer, U.
    Tartare-Deckert, S.
    Raynaud, S. D.
    Cassuto, J. P.
    Ticchioni, M.
    Deckert, M.
    ONCOGENE, 2009, 28 (37) : 3261 - 3273
  • [30] Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies
    Tantawy, Shady I.
    Sarkar, Aloke
    Hubner, Stefan
    Tan, Zhi
    Wierda, William G.
    Eldeib, Abdelraouf
    Zhang, Shuxing
    Kornblau, Steven
    Gandhi, Varsha
    CLINICAL CANCER RESEARCH, 2023, 29 (02) : 446 - 457
12345