Registration-assisted segmentation of real-time 3-D echocardiographic data using deformable models

被引:60
|
作者
Zagrodsky, V
Walimbe, V
Castro-Pareja, CR
Qin, JX
Song, JM
Shekhar, R [1 ]
机构
[1] Cleveland Clin Fdn, Lerner Res Inst, Dept Biomed Engn, Cleveland, OH 44195 USA
[2] Ohio State Univ, Ctr Biomed Engn, Columbus, OH 43210 USA
[3] Univ Maryland, Dept Diagnost Radiol, Baltimore, MD 21201 USA
[4] Howard Univ Hosp, Dept Med, Washington, DC 20060 USA
[5] Cleveland Clin Fdn, Dept Cardiovasc Med, Cleveland, OH 44195 USA
关键词
deformable models; image registration; image segmentation; real-time three-dimensional echocardiography; three-dimensional ultrasound;
D O I
10.1109/TMI.2005.852057
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Real-time three-dimensional (3-D) echocardiography is a new imaging modality that presents the unique opportunity to visualize the complex 3-D shape and motion of the left ventricle (LV) in vivo and to measure the associated global and local function parameters. To take advantage of this opportunity in routine clinical practice, automatic segmentation of the LV in the 3-D echocardiographic data, usually hundreds of megabytes large, is essential. We report a new segmentation algorithm for this task. Our algorithm has two distinct stages, initialization of a deformable model and its refinement, which are connected by a dual "voxel + wiremesh" template. In the first stage, mutual-information-based registration of the voxel template with the image to be segmented helps initialize the wiremesh template. In the second stage, the wiremesh is refined iteratively under the influence of external and internal forces. The internal forces have been customized to preserve the nonsymmetric shape of the wiremesh template in the absence of external forces, defined using the gradient vector flow approach. The algorithm was validated against expert-defined segmentation and demonstrated acceptable accuracy. Our segmentation algorithm is fully automatic and has the potential to be used clinically together with real-time 3-D echocardiography for improved cardiovascular disease diagnosis.
引用
收藏
页码:1089 / 1099
页数:11
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