Double-Headed Nucleotides: Building Blocks for New Nucleic Acid Architectures

被引:15
|
作者
Sharma, Pawan K. [1 ]
Kumar, Pawan [2 ]
Nielsen, Poul [2 ]
机构
[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India
[2] Univ Southern Denmark, Dept Phys Chem & Pharm, Nucle Acid Ctr, DK-5230 Odense, Denmark
基金
新加坡国家研究基金会;
关键词
BASE-BASE INTERACTIONS; MINOR-GROOVE; SECONDARY STRUCTURES; DNA-NANOTECHNOLOGY; MAJOR GROOVE; DUPLEX; OLIGONUCLEOTIDES; NUCLEOBASE; STABILITY; 2ND-MESSENGER;
D O I
10.1071/CH16021
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Double-headed nucleotides are nucleotides with two nucleobases. These have been investigated recently with the purpose of using the recognition potential of the additional nucleobases in various nucleic acid constructs. Presented here is a review of the double-headed nucleotide monomers investigated so far and their effects in nucleic acid duplexes and other secondary structures.
引用
收藏
页码:1094 / 1101
页数:8
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