Total synthesis and absolute configuration of nocardioazine B

被引:41
|
作者
Wang, Mingzhong [1 ]
Feng, Xiangyang [1 ,2 ]
Cai, Liangzhen [2 ]
Xu, Zhengshuang [1 ,3 ]
Ye, Tao [1 ,3 ]
机构
[1] Univ Town Shenzhen, Peking Univ Shenzhen Grad Sch, Lab Chem Genom, Shenzhen 518055, Peoples R China
[2] E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China
[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China
关键词
INDOLE ALKALOID ANALOGS; STEREOCONTROLLED SYNTHESIS; TRYPTOPHAN; REASSIGNMENT; CHEMISTRY;
D O I
10.1039/c2cc31025b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The first total synthesis of the indole alkaloid nocardioazine B was accomplished in 10 steps with an overall yield of 11.8%, establishing the absolute stereochemistry of the natural product.
引用
收藏
页码:4344 / 4346
页数:3
相关论文
共 50 条
  • [31] Total Synthesis and Determination of the Absolute Configuration of (-)-Dolabriferol
    Laclef, Sylvain
    Turks, Maris
    Vogel, Pierre
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (45) : 8525 - 8527
  • [32] Total Synthesis and Determination of the Absolute Configuration of (-)-Idesolide
    Yamakoshi, Hiroyuki
    Shibuya, Masatoshi
    Tomizawa, Masaki
    Osada, Yuji
    Kanoh, Naoki
    Iwabuchi, Yoshiharu
    ORGANIC LETTERS, 2010, 12 (05) : 980 - 983
  • [33] Total synthesis and absolute configuration of malyngamide W
    Qi, Xian-Liang
    Zhang, Jun-Tao
    Feng, Jian-Peng
    Cao, Xiao-Ping
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 9 (10) : 3817 - 3824
  • [34] Total synthesis and determination of the absolute configuration of rakicidin A
    Chen, Yue, 1600, American Chemical Society (136):
  • [35] Verticilide: Elucidation of absolute configuration and total synthesis
    Monma, Souichi
    Sunazuka, Toshiaki
    Nagai, Kenichiro
    Arai, Takahiro
    Shiomi, Kazuro
    Matsui, Ryosuke
    Omura, Satoshi
    ORGANIC LETTERS, 2006, 8 (24) : 5601 - 5604
  • [36] Assignment of the Absolute Configuration and Total Synthesis of (+)-Caripyrin
    Andernach, Lars
    Opatz, Till
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2014, 2014 (22) : 4780 - 4784
  • [37] Total Synthesis and Determination of the Absolute Configuration of Parimycin
    Hsu, Day-Shin
    Huang, Jiun-Yi
    ORGANIC LETTERS, 2019, 21 (18) : 7665 - 7668
  • [38] Total synthesis and determination of the absolute configuration of (+)-intricatetraol
    Morimoto, Yoshiki
    Okita, Tatsuya
    Takaishi, Mamoru
    Tanaka, Takeshi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (07) : 1132 - 1135
  • [39] TOTAL SYNTHESIS AND ABSOLUTE CONFIGURATION OF NATURAL MULTIFLORAMINES
    BROSSI, A
    OBRIEN, J
    TEITEL, S
    HELVETICA CHIMICA ACTA, 1969, 52 (03) : 678 - &
  • [40] Total Synthesis and Determination of the Absolute Configuration of Vinylamycin
    Yang, Zhantao
    Yang, Guang
    Ma, Meiyan
    Li, Jiangnan
    Liu, Jianwei
    Wang, Jinghan
    Jiang, Shende
    Zhang, Quan
    Chen, Yue
    ORGANIC LETTERS, 2015, 17 (23) : 5725 - 5727