Parvovirus B19 Infection and Severe Anemia in Renal Transplant Recipients

被引：8
|
作者：
Carraturo, Antonio [1 ]
Catalani, Valentina [1 ]
Ottaviani, Donatella [2 ]
Menichelli, Patrizia [1 ]
Rossini, Maurizio [3 ]
Terella, Delia [3 ]
Biondi, Brunello [3 ]
机构：
[1] AUSL Latina, Santa Maria Goretti Hosp, Clin Pathol Lab, I-04100 Latina, Italy
[2] Expt Zooprophylact Inst Umbria & Marche IZSUM, CEREM, I-60126 Ancona, Italy
[3] AUSL Latina, Santa Maria Goretti Hosp, Kidney Transplant Unit, I-04100 Latina, Italy
来源：
SCIENTIFIC WORLD JOURNAL | 2012年
关键词：
KIDNEY; DISEASE; HOST;
D O I：
10.1100/2012/102829
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Kidney transplant (KT) recipients can develop symptomatic Parvovirus (PV) B19 infections, frequently associated with persistent anemia. The aim of this study was to evaluate the prevalence and clinical significance of PV B19 infection in anemic and non-anemic KT patients. Overall, out of 64 patients monitored for the presence of PV B19 by real-time PCR, 2 (3.12%) had an active PV B19 infection, in absence of other viral coinfections. The 2 cases occurred in nonanemic kidney transplant patients group (2/50, 4%), while none of the anemic transplant patients (0/14) was found to suffer from this infection. Moreover, patients affected by active PV B19 infection showed viral loads not exceeding 1 x 10(5) genome copies/reaction. In conclusion, in this study, PV B19 infection was not common in renal transplant population and wasn't associated with severe anemia.
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页数：3
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