Application of X-Ray Excited Phosphors in Photodynamic Therapy

被引：2

作者：

Liu, Xiangmei

Tian, Kang

Xue, Chengfeng

Han, Yifan

Liu, Shujuan

Zhao, Qiang ^{[1
]}

机构：

[1] Nanjing Univ Posts & Telecommun, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Key Lab Organ Elect & Informat Displays, IAM, Nanjing 210023, Jiangsu, Peoples R China

来源：

PROGRESS IN CHEMISTRY | 2017年 / 29卷 / 12期

基金：

中国国家自然科学基金;

关键词：

photodynamic therapy; X-ray excited luminescence; nanoscintillator; photosensitizer; energy transfer; MOLYBDENUM CLUSTER; POLYMER DOTS; ZNS CU; LUMINESCENCE; NANOPARTICLES; RADIOTHERAPY; SCINTILLATOR; DOXORUBICIN; ENHANCEMENT; PARTICLES;

D O I：

10.7536/PC170723

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The tissue penetration limitation of excitation light and the absorption wavelength of the photosensitizer hinder the effective treatment of traditional photodynamic therapy (PDT) in deep-seated tumors. Recently, X-ray excited photodynamic therapy (XE-PDT) based on excitation or indirect excitation of photosensitizers via energy transfer by X-ray has attracted a great deal of attention. In this review, recent progress of nanoscintillators, including their rational designs, strategies of photosensitizer loading as well as effects of energy transfer and PDT are summarized The main problems, challenges and future development in deep-seated tumor PDT are also discussed.

引用

页码：1488 / 1498

页数：11

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