Kinetic migration of isothiazolinone biocides from paper packaging to Tenax and Porapak

Migration investigations were carried out on paper packaging materials in contact with solid food simulants. The aim was to investigate the migration behaviour of a series of isothiazolinone biocides (2-methyl-3-isothiazolinone (MI), 1,2-benzisothiazolinone (BIT) and 2-octyl-3-isothiazolinone (OIT)) as potential contaminants in paper materials, at varying temperatures and migration times, for the food simulants Tenax and Porapak. Based on the migration results, Tenax was found to be a good food simulant, and was more suitable than Porapak at high temperature. Petri dishes were found to be suitable for use as migration cells when the compounds to be evaluated were non-volatile. The amount of migration gradually increased with time and increasing temperature, finally reaching a steady value. When the temperature was higher than the boiling point of OIT, the migration rate decreased because of volatilization. The maximum migration rates were 3.4% for MI, 2.2% for BIT and 10.6% for OIT at high temperature (>= 100 degrees C). Two kinds of paper packaging for food were tested with the method that was developed. OIT in the papers migrated into the food simulants but the amount that migrated was less than 0.14 mu g kg(-1).