Multidrug-resistant tuberculosis detection, Latvia

被引:25
|
作者
Skenders, G
Fry, AM
Prokopovica, I
Greckoseja, S
Broka, L
Metchock, B
Holtz, TH
Wells, CD
Leimane, V
机构
[1] Ctr Dis Control & Prevent, Int Res & Programs Branch, Div TB Eliminat, Atlanta, GA 30333 USA
[2] State Ctr TB & Lung Dis, Riga, Latvia
关键词
D O I
10.3201/eid1109.041236
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91 % sensitivity and 96% specificity within 1 to 5 days (vs. 12-47 days for BACTEC).
引用
收藏
页码:1461 / 1463
页数:3
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