Sex Difference of In-hospital Mortality in Patients with Acute Myocardial Infarction

被引:0
|
作者
Shiraki, Teruo [1 ]
Saito, Daiji [1 ]
机构
[1] Natl Hosp Org, Iwakuni Clin Ctr, Dept Cardiol, Yamaguchi 7408510, Japan
关键词
sex difference; acute myocardial infarction; inferior infarction; in-hospital mortality; age difference; GENDER-DIFFERENCES; CLINICAL-OUTCOMES; SHORT-TERM; WOMEN; MEN; PROGNOSIS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Factors contributing to the sex difference of in-hospital mortality after acute myocardial infarction (MI) are still unknown. We compared the clinical characteristics on admission and in-hospital outcome of consecutive 1,354 patients with acute MI between the 2 sexes. Age on admission was about 7 years older in women than in men. In-hospital death was significantly more frequent in women. Pulmonary congestion and hypertension were more likely in women with higher serum levels of total cholesterol and LDL cholesterol. A higher prevalence of current smoking and inferior wall involvement and lower serum HDL cholesterol level were observed in man. After adjusting for age, adverse in-hospital mortality for women was observed in both younger and older patients. Multivariate logistic regression analysis demonstrated that age, location of infarction, recanalization and serum C-reactive protein (CRP) concentration were independent predictors for in-hospital mortality for overall patients, while age and recanalization were independent predictors for male gender, and pulmonary congestion and serum CRP concentration were independent predictors for female gender. In-hospital outcome after acute MI was worse in women. A multivariate logistic regression model revealed that the sexually different factors affected in-hospital mortality in females.
引用
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页码:307 / 314
页数:8
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