An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation

被引：20
|
作者：
Kuraitheerthakumaran, A. [1 ]
Pazhamalai, S. [1 ]
Gopalakrishnan, M. [1 ]
机构：
[1] Annamalai Univ, Dept Chem, Annamalainagar 608002, Tamil Nadu, India
来源：
CHINESE CHEMICAL LETTERS | 2011年 / 22卷 / 10期
关键词：
Hantzsch reaction; 1,4-Dihydropyridine; Microwave; Solvent free; Lanthanum oxide; SCANDIUM TRIFLUOROMETHANESULFONATE; HANTZSCH 1,4-DIHYDROPYRIDINES; IONIC LIQUID; CATALYST; TRIFLATE; ACID;
D O I：
10.1016/j.cclet.2011.05.003
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient synthesis of 1,4-dihydropyridines using lanthanum oxide as a catalyst from aldehydes, beta-ketoester and ammonium acetate without solvent under the irradiation of microwave is described. Compared with the classical Hantzsch reaction, this new method has the advantage of good yield (90-98%) and short reaction time (40-80 s). (C) 2011 M. Gopalakrishnan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：1199 / 1202
页数：4
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