A newly rearranged 2(3→20)abeotaxane diterpene from the bark of Chinese yew, Taxus mairei

被引：11

作者：

Shi, QW ^{[1
]}

Oritani, T ^{[1
]}

Sugiyama, T ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Agr Sci, Div Life Sci, Lab appl Bioorgan Chem,Aoba Ku, Sendai, Miyagi 9818555, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1998年 / 62卷 / 11期

关键词：

Taxus mairei; Taxaceae; rearranged 2(3 -> 20) abeotaxane; bark; taxoid;

D O I：

10.1271/bbb.62.2263

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A newly rearranged 2(3-->20)abeotaxane diterpenoid with a unique 6/10/6 skeleton was isolated from the bark of the Chinese yew, Taxus mairei. The structure was established as being 7 beta,13 alpha-diacetoxy-2 alpha,5 alpha,10 beta-trihydroxy-9-keto-2(3-->20)abeotaxane on the basis of 1-D and 2-D NMR data. The relative stereochemistry was defined from the results of a NOESY experiment. This is the first reported isolation of a rearranged 2(3-->20)abeotaxane from Taxus mairei.

引用

页码：2263 / 2266

页数：4

共 27 条

[21] Three novel bicyclic taxane diterpenoids with verticillene skeleton from the needles of Chinese yew, Taxus chinensis var. mairei
Shi, QW
Oritani, T
Sugiyama, T
PLANTA MEDICA, 1999, 65 (04) : 356 - 359
[22] Three new taxane diterpenoids from seeds of the Chinese yew, Taxus yunnanensis and T-chinensis var. mairei
Shi, QW
Oritani, T
Sugiyama, T
Zhao, D
Murakami, R
PLANTA MEDICA, 1999, 65 (08) : 767 - 770
[23] Inhibitory effect of 13 taxane diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the proliferation of HeLa cervical cancer cells
Liu, Hai-Sheng
Gao, Yu-Huan
Liu, Li-Hong
Liu, Wei
Shi, Qing-Wen
Dong, Mei
Suzuki, Toshikazu
Kiyota, Hiromasa
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2016, 80 (10) : 1883 - 1886
[24] New 14-hydroxy-taxane and 2α,20-epoxy-11(15 → 1)abeotaxane from the needles of Taxus canadensis
Shi, Qing-Wen
Dong, Mei
Huo, Chang-Hong
Su, Xiao-Hui
Li, Cun-Fang
Zhang, Xi-Ping
Wang, Yu-Fang
Kiyota, Hiromasa
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2007, 71 (07) : 1777 - 1780
[25] Structural determination of a new 2(3→20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata
Huo, Changhong
Su, Xiaohui
Li, Xing
Zhang, Xiping
Li, Cunfang
Wang, Yufang
Shi, Qingwen
Kiyota, Hiromasa
MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (06) : 527 - 530
[26] CONSTITUENTS OF THE CULTIVATED MULBERRY TREE .29. STRUCTURES OF 3 NEW 2-ARYLBENZOFURAN DERIVATIVES FROM THE CHINESE CRUDE DRUG SANG-BAI-PI (MORUS ROOT BARK)
HANO, Y
KOHNO, H
ITOH, M
NOMURA, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 1985, 33 (12) : 5294 - 5300
[27] Bioactive constituents of Chinese natural medicines.: VII.: Inhibitors of degranulation in RBL-2H3 cells and absolute stereo structures of three new diarylheptanoid glycosides from the bark of a Myrica rubra
Matsuda, H
Morikawa, T
Tao, J
Ueda, K
Yoshikawa, M
CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (02) : 208 - 215

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