Comparison of automated assays for the determination of vitamin B12 in serum

被引：21
|
作者：
Vogeser, Michael
Lorenzl, Stefan
机构：
[1] Hosp Univ Munich, Inst Clin Chem, D-81377 Munich, Germany
[2] Hosp Univ Munich, Neurol Clin, Munich, Germany
来源：
CLINICAL BIOCHEMISTRY | 2007年 / 40卷 / 16-17期
关键词：
cobalamin; Vitamin B-12; ligand binding assays; method comparison;
D O I：
10.1016/j.clinbiochem.2007.08.004
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Objectives: To study the agreement of serum cobalamin results obtained with three different widely used analyzers. Design and methods: Comparative measurement of 100 serum samples was performed using the Abbott Architect, the Bayer Centaur, and the Roche Elecsys 2010 analyzer. Results: Relatively close numeric correlation of the results was found with Pearson's r>0.95 for all three comparisons; however, the mean concentration of the highest reading and the lowest reading method differed by 16%. Conclusions: Relatively good agreement of results from three automated serum cobalamin assays was observed. (C) 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码：1342 / 1345
页数：4
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