SF3B1 MUTATIONS IN MDS-RS ARISE IN MULTIPOTENT HEMOPOETIC STEM CELLS

被引:0
|
作者
Mortera-Blanco, T. [1 ]
Dimitriou, M. [1 ]
Woll, P. S. [2 ]
Elvarsdottir, E. [1 ]
Karimi, M. [1 ]
Conte, S. [1 ]
Jansson, M. [1 ]
Douagi, I. [1 ]
Papaemmanuil, E. [3 ]
Jacobsen, S. E. [1 ,2 ]
Hellstrom-Lindberg, E. [1 ]
机构
[1] Karolinska Univ Hosp Huddinge, Ctr Hematol & Regenerat Med, Stockholm, Sweden
[2] Univ Oxford, Weatherall Inst Mol Med, Haematopoiet Stem Cell Biol Lab, Oxford, England
[3] Wellcome Trust Sanger Inst, Canc Genome Project, Cambridge, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
S445
引用
收藏
页码:159 / 159
页数:1
相关论文
共 50 条
  • [21] MDS with Deletions in the Long Arm of Chromosome 11 Are Associated with a High Frequency of SF3B1 Mutations
    Stengel, Anna
    Kern, Wolfgang
    Meggendorfer, Manja
    Haferlach, Torsten
    Haferlach, Claudia
    BLOOD, 2016, 128 (22)
  • [22] MDS with deletions in the long arm of chromosome 11 are associated with a high frequency of SF3B1 mutations
    A Stengel
    W Kern
    M Meggendorfer
    T Haferlach
    C Haferlach
    Leukemia, 2017, 31 : 1995 - 1997
  • [23] MDS with deletions in the long arm of chromosome 11 are associated with a high frequency of SF3B1 mutations
    Stengel, A.
    Kern, W.
    Meggendorfer, M.
    Haferlach, T.
    Haferlach, C.
    LEUKEMIA, 2017, 31 (09) : 1995 - 1997
  • [24] SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications
    Shalini Singh
    Doaa Ahmed
    Hamid Dolatshad
    Dharamveer Tatwavedi
    Ulrike Schulze
    Andrea Sanchi
    Sarah Ryley
    Ashish Dhir
    Lee Carpenter
    Suzanne M. Watt
    David J. Roberts
    Amal M. Abdel-Aal
    Sohair K. Sayed
    Somaia A. Mohamed
    Anna Schuh
    Paresh Vyas
    Sally Killick
    Andriana G. Kotini
    Eirini P. Papapetrou
    Daniel H. Wiseman
    Andrea Pellagatti
    Jacqueline Boultwood
    Leukemia, 2020, 34 : 2525 - 2530
  • [25] SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications
    Singh, Shalini
    Ahmed, Doaa
    Dolatshad, Hamid
    Tatwavedi, Dharamveer
    Schulze, Ulrike
    Sanchi, Andrea
    Ryley, Sarah
    Dhir, Ashish
    Carpenter, Lee
    Watt, Suzanne M.
    Roberts, David J.
    Abdel-Aal, Amal M.
    Sayed, Sohair K.
    Mohamed, Somaia A.
    Schuh, Anna
    Vyas, Paresh
    Killick, Sally
    Kotini, Andriana G.
    Papapetrou, Eirini P.
    Wiseman, Daniel H.
    Pellagatti, Andrea
    Boultwood, Jacqueline
    LEUKEMIA, 2020, 34 (09) : 2525 - 2530
  • [26] Hierarchical Analysis Of Recurrent Point Mutations In SF3B1 and TET2 In RARS Stem Cells
    Mortera-Blanco, Teresa
    Dimitriou, Marios
    Woll, Petter
    Karimi, Mohsen
    Papaemmanuil, Elli
    Conte, Simona
    Chowdhuri, Oni
    Jansson, Monika
    Campbell, Peter J.
    Jacobsen, Sten Eirik W.
    Hellstroem-Lindberg, Eva
    BLOOD, 2013, 122 (21)
  • [27] SF3B1 Splicing Mutation in the Context of Therapy Related MDS
    Volpe, Virginia Olivia
    Al Ali, Najla
    Chan, Onyee
    Padron, Eric
    Sallman, David A.
    Komrokji, Rami S.
    BLOOD, 2020, 136
  • [28] A novel SF3B1 variant in a patient with MDS with ring sideroblasts
    Al-Ghamdi, Yahya A.
    Kluk, Michael J.
    EJHAEM, 2022, 3 (03): : 1078 - 1079
  • [29] Cancer-associated mutations in SF3B1 disrupt the interaction between SF3B1 and DDX42
    Zhao, Bo
    Li, Zhuang
    Qian, Rui
    Liu, Gang
    Fan, Mingyue
    Liang, Zehua
    Hu, Xin
    Wan, Youzhong
    JOURNAL OF BIOCHEMISTRY, 2022, 172 (02): : 117 - 126
  • [30] Molecular Genetic Analysis of Myelodysplastic Syndromes (MDS) Patients with Ring Sideroblasts (RS); Independent Confirmation of Association of SF3B1 Mutations with Better Prognosis
    Ali, Abdullah Mahmood
    Iverson, Nicholas
    Penson, Alexander
    Scott, Allison
    Riaz, Tabish
    Rabadan, Raul
    Mukherjee, Siddhartha
    Raza, Azra
    BLOOD, 2014, 124 (21)