In-Vitro Evaluation of Anti-Inflammatory and Anti-Microbial Properties of Ethanolic Extract of Cydonia Oblonga Seeds

Phytochemical, antimicrobial, antioxidant and anti-inflammatory properties of ethanol extract of Cydonia oblonga were studied. The antioxidant and anti-inflammatory efficacy of the extract was assessed through different methods using DPPH and bovine albumin respectively. Total phenolic content (TPC) was estimated using Folin-Cioucalteu reagent. Antimicrobial effect of seeds was studied using disc diffusion method against gram positive and negative bacteria viz; S.aureus, P.aeruginosa and fungi C. albicans. Phyto-chemical analysis showed the presence of alkaloids, phenols, tannins, amino acids, carbohydrate, fats/oils and glycosides. TPC of the seed extract was found to be 37.46 +/- 0.10 mg GAE/gm, extract also showed significant antioxidant and anti-inflammatory activity with IC50 value of 299.98 mu g/ml and 300 mu g/ml respectively. Anti-microbial results indicated that Cydonia oblonga seeds extract is effective against gram positive bacteria.