The Time Trend of Blood Lead and Cadmium Levels in Rural Chinese Children: China Nutrition and Health Survey 2002 and 2012

被引:6
|
作者
Liu, Xiaobing [1 ]
Zhang, Huidi [1 ]
Zhang, Yu [2 ]
Wang, Jun [3 ]
Tan, Hongxing [4 ]
Piao, Jianhua [1 ]
Yang, Lichen [1 ]
Yang, Xiaoguang [1 ]
机构
[1] Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing 100050, Peoples R China
[2] Chinese Ctr Dis Control & Prevent, Beijing 102206, Peoples R China
[3] Shenzhen Polytech, Sch Food & Drug, Shenzhen 518055, Guangdong, Peoples R China
[4] Shenzhen Ctr Chron Dis Control, Shenzhen 518020, Guangdong, Peoples R China
关键词
Lead; Cadmium; Human biomonitoring; Exposure risk; Reference value; HEAVY-METALS; REFERENCE VALUES; NATIONAL-HEALTH; EXPOSURE; ADOLESCENTS; POPULATION; IMPACT; URINE;
D O I
10.1007/s12011-022-03333-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This study was to investigate blood lead (Pb) and cadmium (Cd) levels and time trend in rural Chinese children derived from the China Nutrition and Health Survey 2002 and 2012 (CNHS 2002, CNHS 2012). In total, 1698 and 1581 of rural Chinese children were selected from the CNHS 2002 and the CNHS 2012 databases, respectively. The blood Pb and Cd levels were determined by inductively coupled plasma mass spectrometer (ICP-MS), whilst the prevalence of blood Pb levels >5 mu g/dL and blood Cd levels >0.5 mu g/L and the corresponding reference values (RV(95)s: the upper limit of 95% confidence interval of 95th percentile) were together calculated. From the CNHS 2002 to the CNHS 2012, median concentrations in blood were severally decreased from 6.3 to 3.1 mu g/dL for Pb and from 0.64 to 0.39 mu g/L for Cd. The prevalence of blood Pb levels >5 mu g/dL had decreased from 63.6 to 14.2%, together with blood Cd levels >0.5 mu g/L prevalence from 62.7 to 33.5%, respectively. The RV(95)s of blood Pb and Cd levels were 15.2 mu g/dL and 1.54 mu g/L in the CNHS 2002, as well as 6.3 mu g/dL and 1.12 mu g/L in the CNHS 2012. In conclusion, blood Pb and Cd levels had been obviously improved in rural Chinese children during the past 10 years. However, the risks of Pb and Cd exposure are still serious and required to have continuous health monitoring and evaluation, even call for greater collaboration of the government and society.
引用
收藏
页码:2162 / 2169
页数:8
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