Postmenopausal Osteoporosis

被引:791
|
作者
Black, Dennis M. [1 ]
Rosen, Clifford J. [2 ]
机构
[1] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
[2] Maine Med Ctr, Res Inst, Scarborough, ME USA
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2016年 / 374卷 / 03期
关键词
BONE-MINERAL DENSITY; ZOLEDRONIC ACID; FRACTURE RISK; ANTIRESORPTIVE THERAPY; VERTEBRAL FRACTURES; RANDOMIZED-TRIAL; WOMEN; ALENDRONATE; PREVENTION; HIP;
D O I
10.1056/NEJMcp1513724
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 73-year-old asymptomatic white woman with a history of a Colles fracture of the left radius 10 years earlier presents for evaluation. Dual-energy x-ray absorptiometry reveals a bone mineral density (BMD) T score of -2.8 in the lumbar spine and -2.5 in the total hip. How should this case be managed?This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.
引用
收藏
页码:254 / 262
页数:9
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