Role of non-coding regulatory ribonucleic acids in chronic inflammatory diseases

被引:0
|
作者
Heinz, G. A. [1 ]
Mashreghi, M. -F. [1 ]
机构
[1] Deutsch Rheuma Forschungszentrum DRFZ, Charitepl 1, D-10117 Berlin, Germany
来源
ZEITSCHRIFT FUR RHEUMATOLOGIE | 2016年 / 75卷 / 04期
关键词
MicroRNA; Rheumatoid arthritis; Inflammation; Long non coding RNA; Circular RNA; ARTHRITIS; HOTAIR; RNAS;
D O I
10.1007/s00393-016-0085-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Non-coding regulatory ribonucleic acids (RNA), including microRNA, long non-coding RNA and circular RNA, can influence the expression of genes mediating inflammatory processes and therefore affect the course and progression of chronic inflammatory diseases. Recent studies using antisense oligonucleotides suggest that such non-coding regulatory RNAs are suitable as novel therapeutic target molecules for the treatment of inflammatory rheumatic diseases.
引用
收藏
页码:402 / 405
页数:4
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