Biologically active compounds from Chilean propolis

被引：0
|
作者：
Astudillo, L
Avila, F
Morrison, R
Gutierrez, M
Bastida, J
Codina, C
Schmeda-Hirschmann, G
机构：
[1] Univ Talca, Inst Quim Recursos Nat, Lab Quim Prod Nat, Talca, Chile
[2] Univ Barcelona, Fac Farm, Dept Nat Prod, E-08028 Barcelona, Cataluna, Spain
来源：
BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA | 2000年 / 45卷 / 04期
关键词：
propolis; flavonoids; free radical scavenging activity; DPPH; xanthine oxidase;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A propolis sample from the western Andean slopes of the Maule Region, Chile, showed free radical scavenging activity and inhibited the enzyme xanthine oxidase "in vitro". Six flavonoids were isolated as the main active constituents of the sample. 5,7-dihydroxyflavone 4, 3,5,7-trihydroxyflavone 6 and 5,7-dihydroxyflavanone 1 displayed a strong free radical scavenging effect. At 50 mug/mL, compounds 6 and 1 inhibited the enzyme xanthine oxidase by 95 and 86%, respectively.
引用
收藏
页码：577 / 581
页数：5
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