Enhancing contrast of in-vivo human retinal ganglion cells with multi-offset adaptive optics scanning laser ophthalmoscope

被引:0
|
作者
Gofas-Salas, Elena [1 ,2 ]
Rui, Yuhua [2 ,3 ,4 ]
Mece, Pedro [2 ]
Zhang, Min [2 ]
Snyder, Valerie C. [2 ]
Vienola, Kari V. [2 ]
Lee, Daniel [2 ,5 ]
Sahel, Jose-Alain [2 ]
Rossi, Ethan A. [2 ,5 ,6 ]
Grieve, Kate [1 ]
机构
[1] Quinze Vingts Natl Eye Hosp, 28 Rue Charenton, F-75012 Paris, France
[2] Univ Pittsburgh, Sch Med, Dept Ophthalmol, Pittsburgh, PA 15261 USA
[3] Cent South Univ, Eye Ctr, Xiangya Hosp, Changsha, Hunan, Peoples R China
[4] Hunan Key Lab Ophthalmol, Changsha, Hunan, Peoples R China
[5] Univ Pittsburgh, Dept Bioengn, Swanson Sch Engn, Pittsburgh, PA USA
[6] Univ Pittsburgh, McGowan Inst Regenerat Med, Pittsburgh, PA USA
关键词
D O I
10.1117/12.2614847
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We implement a new adaptive optics scanning laser ophthalmoscope detection path revealing human retinal ganglions with contrast and acquisition time suitable for clinical diagnosis obtaining similar results to what was previously achieved on monkeys. (C) 2021 The Author(s)
引用
收藏
页数:3
相关论文
共 50 条
  • [21] Visualization of Retinal Microstructures by Adaptive Optics Scanning Laser Ophthalmoscope With One-Micrometer Probe
    Sasaki, K.
    Kurokawa, K.
    Makita, S.
    Tamada, D.
    Miura, M.
    Cense, B.
    Yasuno, Y.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [22] The use of forward scatter to improve retinal vascular imaging with an adaptive optics scanning laser ophthalmoscope
    Chui, Toco Y. P.
    VanNasdale, Dean A.
    Burns, Stephen A.
    BIOMEDICAL OPTICS EXPRESS, 2012, 3 (10): : 2537 - 2549
  • [23] Blood Velocity Profile Measurements in Retinal Vessels Using an Adaptive Optics Scanning Laser Ophthalmoscope
    Zhong, Z.
    Chui, T.
    Song, H.
    Petrig, B.
    Burns, S.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [24] Adaptive optics scanning laser ophthalmoscope with integrated wide-field retinal imaging and tracking
    Ferguson, R. Daniel
    Zhong, Zhangyi
    Hammer, Daniel X.
    Mujat, Mircea
    Patel, Ankit H.
    Deng, Cong
    Zou, Weiyao
    Burns, Stephen A.
    JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2010, 27 (11) : A265 - A277
  • [25] Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope
    Li, Hao
    Lu, Jing
    Shi, Guohua
    Zhang, Yudong
    JOURNAL OF BIOMEDICAL OPTICS, 2011, 16 (11)
  • [26] In vivo imaging of retinal ganglion cells in the human eye with adaptive optics optic coherence tomography
    Kadomoto, Shin
    Uji, Akihito
    Muraoka, Yuki
    Tamiya, Ryosuke
    Nozato, Koji
    Tsujikawa, Akitaka
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [27] Spatial-frequency-based image reconstruction to improve image contrast in multi-offset adaptive optics ophthalmoscopy
    Mece, Pedro
    Gofas-Salas, Elena
    Rui, Yuhua
    Zhang, Min
    Sahel, Jose-Alain
    Rossi, Ethan A.
    OPTICS LETTERS, 2021, 46 (05) : 1085 - 1088
  • [28] Handheld Adaptive Optics Scanning Laser Ophthalmoscope for in vivo Photoreceptor Imaging of Supine Adults and Neonates
    DuBose, Theodore
    Nankivil, Derek
    LaRocca, Francesco
    Hagan, Kristen
    Waterman, Gar
    Du Tran-Viet
    Kuo, Anthony N.
    Toth, Cynthia A.
    Izatt, Joseph A.
    Farsiu, Sina
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [29] Bimorph deformable mirror based adaptive optics scanning laser ophthalmoscope for retina imaging in vivo
    王媛媛
    何益
    魏凌
    李喜琪
    杨金生
    周虹
    张雨东
    Chinese Optics Letters, 2017, 15 (12) : 47 - 51
  • [30] Classification of Human Retinal Microaneurysms Using Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography
    Dubow, Michael
    Pinhas, Alexander
    Shah, Nishit
    Cooper, Robert F.
    Gan, Alexander
    Gentile, Ronald C.
    Hendrix, Vernon
    Sulai, Yusufu N.
    Carroll, Joseph
    Chui, Toco Y. P.
    Walsh, Joseph B.
    Weitz, Rishard
    Dubra, Alfredo
    Rosen, Richard B.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (03) : 1299 - 1309