CLEC-2 is not required for platelet aggregation at arteriolar shear

被引:61
|
作者
Hughes, C. E. [1 ]
Navarro-Nunez, L. [1 ]
Finney, B. A. [1 ]
Mourao-Sa, D. [2 ]
Pollitt, A. Y. [1 ]
Watson, S. P. [1 ]
机构
[1] Univ Birmingham, Ctr Cardiovasc Sci, Inst Biomed Res, Coll Med & Dent Sci, Birmingham B15 2TT, W Midlands, England
[2] London Res Inst, Immunobiol Lab, Lincolns Inn Fields Labs, London, England
基金
英国惠康基金;
关键词
LECTIN RECEPTOR CLEC-2; IN-VIVO; ACTIVATION; SYK; INVOLVEMENT; THROMBIN; COLLAGEN; ROLES;
D O I
10.1111/j.1538-7836.2010.04006.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2328 / 2332
页数:5
相关论文
共 50 条
  • [21] Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists
    Clark, Joanne C.
    Martin, Eleyna M.
    Moran, Luis A.
    Di, Ying
    Wang, Xueqing
    Zuidscherwoude, Malou
    Brown, Helena C.
    Kavanagh, Deirdre M.
    Hummert, Johan
    Eble, Johannes A.
    Nieswandt, Bernhard
    Stegner, David
    Pollitt, Alice Y.
    Herten, Dirk-Peter
    Tomlinson, Michael G.
    Garcia, Angel
    Watson, Steve P.
    COMMUNICATIONS BIOLOGY, 2023, 6 (01)
  • [22] TULA-2 Deficiency Enhances Platelet Response to CLEC-2 Agonists
    Kostyak, John
    Mauri, Benjamin R.
    Dangelmaier, Carol A.
    Patel, Akruti
    Zhou, Yuhang
    Tsygankov, Alexander
    McKenzie, Steven Edward
    Kunapuli, Satya P.
    BLOOD, 2017, 130
  • [23] Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI
    Ozaki, Y.
    Suzuki-Inoue, K.
    Inoue, O.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 191 - 194
  • [24] Renal cells activate the platelet receptor CLEC-2 through podoplanin
    Christou, Charita M.
    Pearce, Andrew C.
    Watson, Aleksandra A.
    Mistry, Anita R.
    Pollitt, Alice Y.
    Fenton-May, Angharad E.
    Johnson, Louise A.
    Jackson, David G.
    Watson, Steve P.
    O'Callaghan, Chris A.
    BIOCHEMICAL JOURNAL, 2008, 411 (01) : 133 - 140
  • [25] Novel platelet activation receptor CLEC-2: from discovery to prospects
    Suzuki-Inoue, K.
    Inoue, O.
    Ozaki, Y.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 : 44 - 55
  • [26] Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists
    Joanne C. Clark
    Eleyna M. Martin
    Luis A. Morán
    Ying Di
    Xueqing Wang
    Malou Zuidscherwoude
    Helena C. Brown
    Deirdre M. Kavanagh
    Johan Hummert
    Johannes A. Eble
    Bernhard Nieswandt
    David Stegner
    Alice Y. Pollitt
    Dirk-Peter Herten
    Michael G. Tomlinson
    Angel García
    Steve P. Watson
    Communications Biology, 6
  • [27] CLEC-2/podoplanin and thromboinflammation
    Suzuki-Inoue, Katsue
    BLOOD, 2017, 129 (14) : 1896 - 1898
  • [28] Suppression of platelet aggregation and tumor metastasis by anti-podoplanin mAbs recognizing a novel CLEC-2 binding domain
    Sekiguchi, Takaya
    Takemoto, Ai
    Fujita, Naoya
    CANCER RESEARCH, 2016, 76
  • [29] Molecular Analysis of the Interaction of the Snake Venom Rhodocytin with the Platelet Receptor CLEC-2
    Watson, Aleksandra A.
    O'Callaghan, Christopher A.
    TOXINS, 2011, 3 (08): : 991 - 1003
  • [30] Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2
    Herzog, Brett H.
    Fu, Jianxin
    Wilson, Stephen J.
    Hess, Paul R.
    Sen, Aslihan
    McDaniel, J. Michael
    Pan, Yanfang
    Sheng, Minjia
    Yago, Tadayuki
    Silasi-Mansat, Robert
    McGee, Samuel
    May, Frauke
    Nieswandt, Bernhard
    Morris, Andrew J.
    Lupu, Florea
    Coughlin, Shaun R.
    McEver, Rodger P.
    Chen, Hong
    Kahn, Mark L.
    Xia, Lijun
    NATURE, 2013, 502 (7469) : 105 - +