Microarray based expression profiling of BRCA1 mutated human tumours using a breast-specific platform to identify a profile of BRCA1 deficiency

被引:0
|
作者
Lamers, E. [1 ]
McDyer, F. A. [2 ]
Mulligan, J. M. [2 ]
Couch, F. [3 ]
Savage, K. I. [1 ]
O'Brien, N. E. [1 ]
Mullan, P. B. [1 ]
Kennedy, R. D. [2 ]
Harkin, D. P. [2 ]
Quinn, J. E. [1 ]
机构
[1] Queens Univ Belfast, CCRCB, Belfast BT7 1NN, Antrim, North Ireland
[2] Almac Diagnost, Craigavon, England
[3] Mayo Clin, Rochester, MN USA
关键词
Breast Cancer; Sporadic Breast Cancer; Gene Expression Profile Study; BRCA1 mRNA; Sporadic Breast Cancer Patient;
D O I
10.1186/bcr2541
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:S14 / S14
页数:1
相关论文
共 50 条
  • [41] 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
    Bouwman, Peter
    Aly, Amal
    Escandell, Jose M.
    Pieterse, Mark
    Bartkova, Jirina
    van der Gulden, Hanneke
    Hiddingh, Sanne
    Thanasoula, Maria
    Kulkarni, Atul
    Yang, Qifeng
    Haffty, Bruce G.
    Tommiska, Johanna
    Blomqvist, Carl
    Drapkin, Ronny
    Adams, David J.
    Nevanlinna, Heli
    Bartek, Jiri
    Tarsounas, Madalena
    Ganesan, Shridar
    Jonkers, Jos
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2010, 17 (06) : 688 - U56
  • [42] Androgen receptor expression in patients with BRCA1/2-positive and BRCA1/2-negative breast cancer
    Pristauz, G.
    Petru, E.
    Stacher, E.
    Geigl, J.
    Speicher, M.
    Winter, R.
    Moinfar, F.
    GYNECOLOGIC ONCOLOGY, 2010, 116 (03) : S26 - S26
  • [43] Immunohistochemical profile of hereditary breast cancer not attributable to BRCA1 and BRCA2 mutations. A tissue microarray study
    Palacios, J
    Honrado, E
    Rivas, C
    Lerma, E
    Sanchez, L
    Diez, O
    Alonso, MC
    Prat, J
    Benitez, J
    LABORATORY INVESTIGATION, 2003, 83 (01) : 42A - 42A
  • [44] Immunohistochemical profile of hereditary breast cancer not attributable to BRCA1 and BRCA2 mutations. A tissue microarray study
    Palacios, J
    Honrado, E
    Rivas, C
    Lerma, E
    Sanchez, L
    Diez, O
    Alonso, MC
    Prat, J
    Benitez, JW
    MODERN PATHOLOGY, 2003, 16 (01) : 42A - 42A
  • [45] Validation of the BRCA1 antibody MS110 and the utility of BRCA1 as a patient selection biomarker in immunohistochemical analysis of breast and ovarian tumours
    Milner, Roy
    Wombwell, Helen
    Eckersley, Sonia
    Barnes, Donna
    Warwicker, Juli
    Van Dorp, Erica
    Dearden, Simon
    Hughes, Glen
    Harbron, Chris
    Wellings, Bob
    Hodgson, Darren
    Womack, Chris
    Gray, Neil
    Lau, Alan
    O'Connor, Mark J.
    Marsden, Catherine
    Kvist, Alexander J.
    VIRCHOWS ARCHIV, 2013, 462 (03) : 269 - 279
  • [46] Validation of the BRCA1 antibody MS110 and the utility of BRCA1 as a patient selection biomarker in immunohistochemical analysis of breast and ovarian tumours
    Roy Milner
    Helen Wombwell
    Sonia Eckersley
    Donna Barnes
    Juli Warwicker
    Erica Van Dorp
    Simon Dearden
    Glen Hughes
    Chris Harbron
    Bob Wellings
    Darren Hodgson
    Chris Womack
    Neil Gray
    Alan Lau
    Mark J. O’Connor
    Catherine Marsden
    Alexander J. Kvist
    Virchows Archiv, 2013, 462 : 269 - 279
  • [47] Expression and function of BRCA1 and BRCA2 in familial and sporadic breast cancer
    Barnes, DM
    HISTOPATHOLOGY, 1999, 34 (02) : 170 - 174
  • [48] Association of loss of BRCA1 expression with centrosome aberration in human breast cancer
    Atsushi Shimomura
    Yasuo Miyoshi
    Tetsuya Taguchi
    Yasuhiro Tamaki
    Shinzaburo Noguchi
    Journal of Cancer Research and Clinical Oncology, 2009, 135 : 421 - 430
  • [49] Association of loss of BRCA1 expression with centrosome aberration in human breast cancer
    Shimomura, Atsushi
    Miyoshi, Yasuo
    Taguchi, Tetsuya
    Tamaki, Yasuhiro
    Noguchi, Shinzaburo
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2009, 135 (03) : 421 - 430
  • [50] BRCA1 expression and molecular alterations in familial breast cancer
    Mangia, Anita
    Chiriatti, Annalisa
    Tommasi, Stefania
    Menolascina, Filippo
    Petroni, Stella
    Zito, Francesco A.
    Simone, Giovanni
    Schittulli, Francesco
    Paradiso, Angelo
    HISTOLOGY AND HISTOPATHOLOGY, 2009, 24 (01) : 69 - 76