Cell competition between wild-type and JAK2V617F mutant cells in a murine model of a myeloproliferative neoplasm

被引：4
|
作者：
Castiglione, Melissa [1 ]
Zhang, Haotian [2 ]
Kaushansky, Kenneth [3 ]
Zhan, Huichun [1 ,4 ]
机构：
[1] Stony Brook Sch Med, Dept Med, HSC T15,Room 053, Stony Brook, NY 11794 USA
[2] SUNY Stony Brook, Grad Program Mol & Cellular, Stony Brook, NY 11794 USA
[3] Stony Brook Sch Med, Hlth Sci, Stony Brook, NY USA
[4] Northport VA Med Ctr, Med Serv, Northport, NY 11768 USA
来源：
EXPERIMENTAL HEMATOLOGY | 2021年 / 100卷
关键词：
HEMATOPOIETIC STEM; ENDOTHELIAL-CELLS; CLONAL HEMATOPOIESIS; SOMATIC MUTATIONS; PROGENITOR CELLS; TRANSPLANTATION; MYELOFIBROSIS; EXPANSION; CANCER; CONTRIBUTES;
D O I：
10.1016/j.exphem.2021.06.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：52 / 62
页数：11
相关论文
共 50 条
  • [41] The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling
    Olschok, Kathrin
    Altenburg, Bianca
    de Toledo, Marcelo A. S.
    Maurer, Angela
    Abels, Anne
    Beier, Fabian
    Gezer, Deniz
    Isfort, Susanne
    Paeschke, Katrin
    Bruemmendorf, Tim H.
    Zenke, Martin
    Chatain, Nicolas
    Koschmieder, Steffen
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [42] CALR mutations screening in wild type JAK2V617F and MPLW515K/L Brazilian myeloproliferative neoplasm patients
    Teixeira Nunes, Daniela Prudente
    de Lima, Luciene Terezina
    Chauffaille, Maria de Lourdes
    Mitne-Neto, Miguel
    dos Santos, Marcos Tadeu
    Cliquet, Marcelo Gil
    Guerra-Shinohara, Elvira Maria
    BLOOD CELLS MOLECULES AND DISEASES, 2015, 55 (03) : 236 - 240
  • [43] The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms
    Holmstrom, M. O.
    Hjortso, M. D.
    Ahmad, S. M.
    Met, O.
    Martinenaite, E.
    Riley, C.
    Straten, P.
    Svane, I. M.
    Hasselbalch, H. C.
    Andersen, M. H.
    LEUKEMIA, 2017, 31 (02) : 495 - 498
  • [44] Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm
    Yang, Yue
    Akada, Hajime
    Nath, Dipmoy
    Hutchison, Robert E.
    Mohi, Golam
    BLOOD, 2016, 127 (26) : 3410 - 3423
  • [45] The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms
    M O Holmström
    M D Hjortsø
    S M Ahmad
    Ö Met
    E Martinenaite
    C Riley
    P Straten
    I M Svane
    H C Hasselbalch
    M H Andersen
    Leukemia, 2017, 31 : 495 - 498
  • [46] Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model
    Bianco, Thiago Mantello
    Coelho-Silva, Juan L.
    Pereira-Martins, Diego A.
    Scheucher, Priscila Santos
    Weinhauser, Isabel
    Alves Silva, Antonio Bruno
    Silva, Cleide Lucia
    Mullally, Ann
    Kobayashi, Susumu S.
    Rego, Eduardo M.
    Traina, Fabiola
    Figueiredo-Pontes, Lorena Lobo
    BLOOD, 2019, 134
  • [47] Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2V617F myeloproliferative neoplasm patients
    Calzada, Ariel Amaru
    Pedrini, Olga
    Finazzi, Guido
    Leoni, Flavio
    Mascagni, Paolo
    Introna, Martino
    Rambaldi, Alessandro
    Golay, Josee
    EXPERIMENTAL HEMATOLOGY, 2013, 41 (03) : 253 - 260
  • [48] THE HDACI GIVINOSTAT MODULATES HEMATOPOIETIC TRANSCRIPTION FACTORS IN JAK2V617F CELLS FROM MYELOPROLIFERATIVE NEOPLASM PATIENTS
    Calzada, A. Amaru
    HAEMATOLOGICA, 2012, 97 : 373 - 373
  • [49] Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm
    Poisson, Johanne
    Tanguy, Marion
    Davy, Hortense
    Camara, Fatoumata
    El Mdawar, Marie-Belle
    Kheloufi, Marouane
    Dagher, Tracy
    Devue, Cecile
    Lasselin, Juliette
    Plessier, Aurelie
    Merchant, Salma
    Blanc-Brude, Olivier
    Souyri, Michele
    Mougenot, Nathalie
    Dingli, Florent
    Loew, Damarys
    Hatem, Stephane N.
    James, Chloe
    Villeval, Jean-Luc
    Boulanger, Chantal M.
    Rautou, Pierre-Emmanuel
    JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (05): : 2630 - 2643
  • [50] JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML
    Dagher, Tracy
    Maslah, Nabih
    Edmond, Valerie
    Cassinat, Bruno
    Vainchenker, William
    Giraudier, Stephane
    Pasquier, Florence
    Verger, Emmanuelle
    Niwa-Kawakita, Michiko
    Lallemand-Breitenbach, Valerie
    Plo, Isabelle
    Kiladjian, Jean-Jacques
    Villeval, Jean-Luc
    de The, Hugues
    JOURNAL OF EXPERIMENTAL MEDICINE, 2021, 218 (02):
12345