Antiplatelet agents for the treatment and prevention of atherothrombosis

被引：170

作者：

Patrono, Carlo ^{[1
]}

Andreotti, Felicita ^{[2
]}

Arnesen, Harald ^{[3
]}

Badimon, Lina ^{[4
]}

Baigent, Colin ^{[5
,6
]}

Collet, Jean-Philippe ^{[7
]}

De Caterina, Raffaele ^{[8
,9
]}

Gulba, Dietrich ^{[10
]}

Huber, Kurt ^{[11
]}

Husted, Steen

Kristensen, Steen Dalby

Morais, Joao ^{[13
]}

Neumann, Franz-Josef ^{[14
]}

Rasmussen, Lars Hvilsted ^{[12
]}

Siegbahn, Agneta ^{[15
,16
]}

Steg, Philippe-Gabriel ^{[17
]}

Storey, Robert F. ^{[18
]}

Van de Werf, Frans ^{[19
]}

Verheugt, Freek ^{[20
]}

机构：

[1] Catholic Univ Sch Med, Dept Pharmacol, I-00168 Rome, Italy

[2] Catholic Univ Sch Med, Dept Cardiovasc Med, I-00168 Rome, Italy

[3] Oslo Univ Hosp, Ctr Clin Heart Res, Dept Cardiol, Oslo, Norway

[4] Hosp Santa Creu & Sant Pau, Cardiovasc Res Ctr CSIS ICCC, CiberOBN Inst Carlos III, Barcelona, Spain

[5] Univ Oxford, Clin Trial Serv Unit, Oxford, England

[6] Univ Oxford, Epidemiol Studies Unit, Oxford, England

[7] Grp Hosp Pitie Salpetriere, INSERM, U937, Inst Cardiol, F-75634 Paris, France

[8] G Monasterio Fdn Med Res, Pisa, Italy

[9] Univ G dAnnunzio, Chieti, Italy

[10] Krankenhaus Duren, Dept Cardiol, Duren, Germany

[11] Wilhelminenhospital, Dept Med Cardiol & Emergency Med 3, Vienna, Austria

[12] Aarhus Univ Hosp, Dept Cardiol, Aalborg Hosp, DK-8000 Aarhus, Denmark

[13] Santo Andres Hosp, Div Cardiol, Leiria, Portugal

[14] Herz Zentrum Bad Krozingen, Dept Cardiol, Bad Krozingen, Germany

[15] Uppsala Univ, Dept Med Sci, Uppsala, Sweden

[16] Uppsala Univ, Uppsala Clin Res Ctr, Uppsala, Sweden

[17] Univ Paris 07, INSERM, Hop Bichat, U698, Paris, France

[18] Univ Sheffield, Dept Cardiovasc Sci, Sheffield, S Yorkshire, England

[19] Univ Louvain, Dept Cardiovasc Med, Louvain, Belgium

[20] Radboud Univ Nijmegen, Med Ctr, Fac Med Sci, NL-6500 HB Nijmegen, Netherlands

来源：

EUROPEAN HEART JOURNAL | 2011年 / 32卷 / 23期

关键词：

Atherothrombosis; Antiplatelet drugs; Aspirin; Clopidogrel; Dipyridamole; Prasugrel; Ticagrelor; Ticlopidine; ACUTE CORONARY SYNDROMES; ACUTE MYOCARDIAL-INFARCTION; LOW-DOSE ASPIRIN; EXPERT CONSENSUS DOCUMENT; ACTIVATED RECEPTOR 1; DOUBLE-BLIND; PLATELET INHIBITION; EUROPEAN-SOCIETY; UNSTABLE ANGINA; TASK-FORCE;

D O I：

10.1093/eurheartj/ehr373

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical pharmacology of antiplatelet drugs has been reviewed previously by the European Society of Cardiology (ESC) Task force and by the 8th American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines. Moreover, information on the efficacy and safety of antiplatelet drugs in the treatment and prevention of atherothrombosis is provided by collaborative meta-analyses of 287 secondary prevention trials and 6 primary prevention trials. The present document intends to provide practicing physicians with an updated instrument to guide their choice of the most suitable antiplatelet strategy for the individual patient at risk, or with different clinical manifestations, of atherothrombosis.

引用

页码：2922 / 2933B

页数：13

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