Clonal distribution of multidrug-resistant Enterobacter cloacae

被引：31

作者：

Girlich, Delphine ^{[1
]}

Poirel, Laurent ^{[1
,2
]}

Nordmann, Patrice ^{[1
,2
,3
]}

机构：

[1] INSERM, Emerging Resistance Antibiot U914, K Bicetre, France

[2] Univ Fribourg, Fac Sci, Dept Med, Med & Mol Microbiol, CH-1700 Fribourg, Switzerland

[3] Hop Cantonal Fribourg, Hop Fribourgeois, Fribourg, Switzerland

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2015年 / 81卷 / 04期

关键词：

Multidrug-resistant bacteria; Prevalence; MLST; Enterobacter cloacae; INTENSIVE-CARE-UNIT; BETA-LACTAMASE; OUTBREAK;

D O I：

10.1016/j.diagmicrobio.2015.01.003

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A multilocus sequence typing (MIST) scheme including 7 housekeeping genes was used to evaluate whether the current spread of multidrug-resistant Enterobacter cloacae isolates worldwide might be associated to specific successful clones. Fifty E. cloacae clinical isolates of worldwide origin, with various beta-lactamase content, and recovered at different periods of time were studied. Forty-four sequence types were identified, highlighting a high clonal diversity with 3 main lineages. This study revealed that a precise identification of the isolates by sequencing of the chromosomal ampC gene of E. cloacae would provide a significant added value to improve the reliability of the MLST scheme. (C) 2015 Elsevier Inc. All rights reserved.

引用

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页码：264 / 268

页数：5

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